Protein Alignment drl and igf1ra

DIOPT Version :10

• Sequence 1: NP_001260566.1
• Gene: drl / 44355
• FlyBaseID: FBgn0015380
• Length: 645
• Species: Drosophila melanogaster
• Sequence 2: XP_073784886.1
• Gene: igf1ra / 245701
• ZFINID: ZDB-GENE-020503-1
• Length: 1433
• Species: Danio rerio
• Alignment Length: 377
• Identity: 105/377 - (27%)
• Similarity: 191/377 - (50%)
• Gaps: 55/377 - (14%)

  Fly   237 VPPA------SGLVTLIVGGILALVLVSTLILIAYCAKGPSKRHPSNGVHLIKTSSFQRLPTISS 295
            |||.      :..|.:|:..|:.|:|:..::.:....|..:.....|||
Zfish   949 VPPPKRNYDNAFYVAIIIPVIVLLLLLFVIVAVIIVTKKRNSDRIGNGV---------------- 997

  Fly   296 TAHNSIYVCPSTITPTYATLTRPFREYEHEPEEFNRRLQELTVQKCRVRLSCLVQEGNFGRIY-- 358
                 :|   :::.|.|.:   ||..|  .|:|:....:::|:  ||.     :.:|:||.:|
Zfish   998 -----LY---ASVNPEYFS---PFEMY--VPDEWEVAREKITM--CRE-----LGQGSFGMVYEG 1042

  Fly   359 --RGTYNDCQE--VLVKTVAQHASQLQVNLLLQESMMLYEASHPNVLSVLGISIEDYATPFVLYA 419
              :|...|..|  |.:|||.:.||..:....|.|:.::.|.:..:|:.:||:..:...|..::..
Zfish  1043 IAKGVVKDEPETRVAIKTVNESASVRERIEFLNEASVMKEFNCHHVVRLLGVVSQGQPTLVIMEL 1107

  Fly   420 AT-----GSVRNLKSFLQDPSYARSVTTIQTVL-MGSQLAMAMEHLHNHGVIHKDIAARNCVIDD 478
            .|     ..:|:|:|..|..| ::|:..::.:: |..::|..|.:|:.:..:|:|:|||||::.:
Zfish  1108 MTRGDLKSHLRSLRSKEQGSS-SQSLPPLKKMIQMAGEIADGMAYLNANKFVHRDLAARNCMVAE 1171

  Fly   479 QLRVKLTDSALSRDLFPGDYNSLGDGEYRPIKWLSLEALQKSHYNEGSDVWSFGVLMWEMCTLGK 543
            ...||:.|..::||::..||...|.....|::|:|.|:|:...:...||||||||::||:.||.:
Zfish  1172 DFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGVFTTNSDVWSFGVVLWEIATLAE 1236

  Fly   544 LPYAEIDPYEMEHYLKDGYRLAQPFNCPDELFTIMAYCWASMPAERPSFSQL 595
            .||..:...::..::.:|..|.:|.||||.||.:|..||...|..||||.::
Zfish  1237 QPYQGMSNEQVLRFVMEGGLLDKPDNCPDMLFELMRMCWQYNPKMRPSFLEI 1288

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
drl	NP_001260566.1	WIF	21..157	CDD:128745
		PTK_Ryk	336..606	CDD:270639	85/272 (31%)
igf1ra	XP_073784886.1	None