Sequence 1: | NP_001260566.1 | Gene: | drl / 44355 | FlyBaseID: | FBgn0015380 | Length: | 645 | Species: | Drosophila melanogaster |
---|---|---|---|---|---|---|---|---|---|
Sequence 2: | NP_005219.2 | Gene: | EGFR / 1956 | HGNCID: | 3236 | Length: | 1210 | Species: | Homo sapiens |
Alignment Length: | 399 | Identity: | 105/399 - (26%) |
---|---|---|---|
Similarity: | 169/399 - (42%) | Gaps: | 86/399 - (21%) |
- Green bases have known domain annotations that are detailed below.
Fly 238 PPASGLVTLIVGGILALVLVSTLILIAYCAKGPSKRHPSNGVHLIKTSSFQRL--------PTIS 294
Fly 295 STAHNSIYVCPSTITPTYATLTRPFREYEHEPEEFNRRLQELTVQKCRVRLSCLVQEGNFGRIYR 359
Fly 360 GTYNDCQE-----VLVKTVAQHASQLQVNLLLQESMMLYEASHPNVLSVLGISIEDYATPFVLYA 419
Fly 420 ATGSVRNLKSFLQDP-----SYARSVTTIQTVLMGS--------QLAMAMEHLHNHGVIHKDIAA 471
Fly 472 RNCVIDDQLRVKLTDSALSRDLFPGDYNSLGDGEYRPIKWLSLEALQKSHYNEGSDVWSFGVLMW 536
Fly 537 EMCTLGKLPYAEIDPYEMEHYLKDGYRLAQPFNCPDELFTIMAYCWASMPAERPSFSQLQICLSE 601
Fly 602 FHTQITRYV 610 |
Gene | Sequence | Domain | Region | External ID | Identity |
---|---|---|---|---|---|
drl | NP_001260566.1 | WIF | 21..157 | CDD:128745 | |
PTK_Ryk | 336..606 | CDD:270639 | 81/287 (28%) | ||
Pkinase_Tyr | 343..599 | CDD:285015 | 79/273 (29%) | ||
EGFR | NP_005219.2 | Recep_L_domain | 57..168 | CDD:279382 | |
Approximate | 75..300 | ||||
Furin-like | 185..335 | CDD:279142 | |||
FU | 231..274 | CDD:238021 | |||
Recep_L_domain | 361..481 | CDD:279382 | |||
Approximate | 390..600 | ||||
GF_recep_IV | 505..637 | CDD:291509 | |||
FU | 506..559 | CDD:238021 | |||
FU | 552..598 | CDD:214589 | |||
TM_ErbB1 | 634..677 | CDD:213054 | 11/46 (24%) | ||
Important for dimerization, phosphorylation and activation | 688..704 | 5/26 (19%) | |||
PTKc_EGFR | 704..1016 | CDD:270683 | 87/314 (28%) | ||
TyrKc | 713..968 | CDD:197581 | 80/277 (29%) | ||
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1097..1137 | ||||
Blue background indicates that the domain is not in the aligned region. |
Tool | Simple Score | Weighted Score | Original Tool Information | |||
---|---|---|---|---|---|---|
BLAST Result | Score | Score Type | Cluster ID | |||
Compara | 0 | 0.000 | Not matched by this tool. | |||
Domainoid | 0 | 0.000 | Not matched by this tool. | |||
eggNOG | 1 | 0.900 | - | - | E1_KOG1025 | |
Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
Homologene | 0 | 0.000 | Not matched by this tool. | |||
Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
Isobase | 0 | 0.000 | Not matched by this tool. | |||
OMA | 0 | 0.000 | Not matched by this tool. | |||
OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
Panther | 0 | 0.000 | Not matched by this tool. | |||
Phylome | 0 | 0.000 | Not matched by this tool. | |||
RoundUp | 0 | 0.000 | Not matched by this tool. | |||
SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
TreeFam | 0 | 0.000 | Not matched by this tool. | |||
User_Submission | 0 | 0.000 | Not matched by this tool. | |||
1 | 0.900 |