Protein Alignment drl and ZK622.1

DIOPT Version :10

• Sequence 1: NP_001260566.1
• Gene: drl / 44355
• FlyBaseID: FBgn0015380
• Length: 645
• Species: Drosophila melanogaster
• Sequence 2: NP_494994.1
• Gene: ZK622.1 / 191366
• WormBaseID: WBGene00022780
• Length: 419
• Species: Caenorhabditis elegans
• Alignment Length: 328
• Identity: 86/328 - (26%)
• Similarity: 163/328 - (49%)
• Gaps: 41/328 - (12%)

  Fly   281 LIKTSSFQRLPTISSTAHNSIYVCPSTITPTYATLTRPFREYEHEPEEFNRRLQELTVQKCRVRL 345
            ::.|...:|||..::        ||       |.|..|..:            |:..::..:::|
 Worm   103 MVTTLRMKRLPVSAN--------CP-------ALLLNPINK------------QDWELRHDQIKL 140

  Fly   346 SCLVQEGNFGRIYRGTY---NDCQEVLVKTVAQH---ASQLQVNLLLQESMMLYEASHPNVLSVL 404
            ..::.||.||.:|:..:   .:.:.|.||....:   :::..:..:.:|:.::.:..||||:...
 Worm   141 GKMLGEGAFGGVYKAAFYCKGEKRMVAVKVNKGNEKISTRAMIEDVCKEARIMRQYQHPNVVCFF 205

  Fly   405 GISIEDYATPFVLYAATGSVRNLKSFLQDPSYARSVTTIQTVLMGSQLAMAMEHLHNHGVIHKDI 469
            |:.:|  ..|.:|.....|...|.|||::..  .:|:....:......:..:|:||.||.||:|:
 Worm   206 GVCVE--KEPIMLVMELASQGALDSFLKNEK--NNVSLRDKLKYSFDASKGLEYLHQHGCIHRDV 266

  Fly   470 AARNCVIDDQLRVKLTDSALSRDLFPGDYN-SLGDGEYR-PIKWLSLEALQKSHYNEGSDVWSFG 532
            ||||.::...: ||:||..||:.|....:. .|.|.:.: ||:||:.|.:..:.|...|||:|||
 Worm   267 AARNFLMHKNV-VKITDFGLSKQLSDLAHKYKLKDIQAKLPIRWLAPEVIVTATYTFKSDVYSFG 330

  Fly   533 VLMWEMCTLGKLPYAEIDPYEMEHYLKDGYRLAQPFNCPDELFTIM-AYCWASMPAERPSFSQLQ 596
            :|:||:...|.:||..:...|::..:|:|||:..|...|..:..|| :.||...|.:|.:.::::
 Worm   331 ILLWEIFMDGAIPYPGMKLAEVKQKVKNGYRMDAPDRMPAFVRNIMISQCWPQNPEDRGNMNEIR 395

  Fly   597 ICL 599
            :.:
 Worm   396 LAM 398

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
drl	NP_001260566.1	WIF	21..157	CDD:128745
		PTK_Ryk	336..606	CDD:270639	76/273 (28%)
ZK622.1	NP_494994.1	SH2_Fps_family	25..114	CDD:198224	3/10 (30%)
		TyrKc	138..398	CDD:197581	76/264 (29%)