Protein Alignment drl and nipi-4

DIOPT Version :9

• Sequence 1: NP_001260566.1
• Gene: drl / 44355
• FlyBaseID: FBgn0015380
• Length: 645
• Species: Drosophila melanogaster
• Sequence 2: NP_505028.3
• Gene: nipi-4 / 179167
• WormBaseID: WBGene00077712
• Length: 396
• Species: Caenorhabditis elegans
• Alignment Length: 420
• Identity: 91/420 - (21%)
• Similarity: 161/420 - (38%)
• Gaps: 125/420 - (29%)

  Fly   254 LVLVSTLILIA---YCAKGPSKRHPSNGVHLIKTSSFQRLPTISSTAHNSIYVCPSTITPTYATL 315
            ::.:|.|.|:|   :|.|......|.:                     :|||       |....|
 Worm    27 VIAMSGLYLLAIFYFCKKSKKMCQPMS---------------------DSIY-------PYQKRL 63

  Fly   316 TRPFREYEHEPEEFNRRLQELTVQKCRVRLSCLVQEGNFGR-----IYRGTYNDCQEVLVKT--- 372
            |:..||.:      |..:.|.:::         |.:...|:     |:||      .|..||
 Worm    64 TQLERELK------NYLIDEESIE---------VDDFQIGQTADGFIFRG------GVFPKTRNR 107

  Fly   373 -VAQHASQLQVNL--------LLQESMMLYEASHPNVLSVLGISIEDYAT--PFVL--YAATGSV 424
             .|:..:.::::.        ||::::.|.:..|||::.:|.:|...:..  |.:.  :...|::
 Worm   108 FNAKVTTAVKISFPIVSKSISLLEDALRLSKLDHPNLIRLLAVSQLSFTVFRPMIALEWLPGGTL 172

  Fly   425 RNLKSFL---QDPSYARSVTTIQTVLMGSQLAMAMEHLHN------HGVIHKDIAARNCVIDD-- 478
            .:...|.   :|.|....:.....:.:..|::.|::::|:      ..:.|..|..||.::.:
 Worm   173 ADYFQFKVREKDDSERSPIQLKDMLSILYQVSQALKYIHSQLDEFGQELTHGRIFTRNVLVTEPD 237

  Fly   479 --QLRVKLTDSALSRDLFPGDYNSLGDG--------EYRPIKWLSLEALQKSHYNEGSDVWSFGV 533
              :..|||           ||:.....|        .|.|.:.|........|..| :|||.|||
 Worm   238 LRKCEVKL-----------GDFGDAPMGLEYSTPIIAYMPPEILCCAERIPPHRPE-NDVWMFGV 290

  Fly   534 LMWEMCTLGKLPYAEIDPYEMEHYLKDGYRLAQ-----PFNCPDELFTIMAYCWASMPAERPSF- 592
            .:||..|||..|:......|    :|..:||..     |..||.:::|:::.| .|.|..||.|
 Worm   291 FIWECLTLGAQPHFRKSVEE----IKKSFRLPDRGLSCPPTCPLDVWTLVSDC-LSEPHMRPRFA 350

  Fly   593 ----SQLQICLSEFHTQITRYVXPAVLKHA 618
                :.:...|||.|    ..| ||:..:|
 Worm   351 STTNASITSRLSELH----HIVSPALFLYA 376

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
drl	NP_001260566.1	WIF	21..157	CDD:128745
		PTK_Ryk	336..606	CDD:270639	70/321 (22%)
		Pkinase_Tyr	343..599	CDD:285015	66/307 (21%)
nipi-4	NP_505028.3	PKc_like	86..350	CDD:304357	64/286 (22%)
		Pkinase_Tyr	87..350	CDD:285015	64/285 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1025
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900