Protein Alignment drl and si:ch73-383l1.1

DIOPT Version :9

• Sequence 1: NP_001260566.1
• Gene: drl / 44355
• FlyBaseID: FBgn0015380
• Length: 645
• Species: Drosophila melanogaster
• Sequence 2: XP_021331611.1
• Gene: si:ch73-383l1.1 / 101885162
• ZFINID: ZDB-GENE-121214-64
• Length: 1392
• Species: Danio rerio
• Alignment Length: 537
• Identity: 127/537 - (23%)
• Similarity: 207/537 - (38%)
• Gaps: 119/537 - (22%)

  Fly   149 FKRKKICLRE------------------EQDSAHEEYDDDDLDLLQTARKGHGGD-----IHYVD 190
            |.|.:.|:|.                  |.||..|:.:|..|..     .|.|.|     :|..|
Zfish   525 FSRGRTCVRSCNLYNGDVREFANGSTCVECDSQCEKAEDKSLTC-----HGPGPDHCVKCLHLKD 584

  Fly   191 -RNDEHVVANGHQA--------PEKQ------RPVVTESPVGRGNSGGSKRDFDPML-RENLVPP 239
             .|......:|.|.        ||..      .|..|:     |.:|...:|...:| |..|:
Zfish   585 GPNCVEKCPDGLQGANSFIFKYPETNNECHPCHPNCTQ-----GCTGPRIQDCIGILDRTPLI-- 642

  Fly   240 ASGLVTLIVGGILALVLVSTLILIAYCAKGPSKRHPSNGVHLIKTSSFQRLPTISSTAHNSIYVC 304
            |:|    ::||:..:|:|:....|.:..|...|:....  ..::|...:.|             .
Zfish   643 AAG----VIGGMFVVVIVALGFAIFFRRKSIKKKRALR--RFLETELVEPL-------------T 688

  Fly   305 PSTITPTYATLTRPFREYEHEPEEFNRRLQELTVQKCRVRLSCLVQEGNFGRIYRGTYNDCQEVL 369
            ||...|..|.|               |.|:|..:::.::     :..|.||.:|:|.:....|.:
Zfish   689 PSGTAPNQAQL---------------RILKETELKRVKI-----LGTGAFGTVYKGIWVPEGETV 733

  Fly   370 VKTVA----QHASQLQVNL-LLQESMMLYEASHPNVLSVLGISIEDYATPFVLYAATGSVRNLKS 429
            ...||    ..::..:.|: .:.|::::....||:::.:||:.:.............|.:.:...
Zfish   734 KIPVAIKILNESTGPKANVEFMDEALIMASMEHPHLVRLLGVCLSPTIQLVTQLMPHGCLLDYVH 798

  Fly   430 FLQDPSYARSVTTIQTVLMGSQL--------AMAMEHLHNHGVIHKDIAARNCVIDDQLRVKLTD 486
            ..||.             :||||        |..|.:|....::|:|:||||.::.....:|:||
Zfish   799 EHQDN-------------IGSQLLLNWCVQIAKGMMYLEERRLVHRDLAARNVLVKSPNHIKITD 850

  Fly   487 SALSRDLFPGDYNSLGDGEYRPIKWLSLEALQKSHYNEGSDVWSFGVLMWEMCTLGKLPYAEIDP 551
            ..|:|.|...:.....|....||||::||.:....:...|||||:||.:||:.|.|..||..|..
Zfish   851 FGLARLLETNEKEYSADEGKMPIKWMALECIHYRKFTHQSDVWSYGVTIWELMTFGGKPYDGIPT 915

  Fly   552 YEMEHYLKDGYRLAQPFNCPDELFTIMAYCWASMPAERPSFSQLQICLSEFHTQITRYVXPAVLK 616
            .|:...|:.|.||.||..|..:::.:|..||......||.|.:|....|.......||:   |::
Zfish   916 REIPDILEKGERLPQPPICTIDVYMVMVKCWMIDADSRPRFKELAAEFSRMARDPQRYL---VIQ 977

  Fly   617 HAKTCKYNKRRRRKIFQ 633
            .....|.......|.||
Zfish   978 GDDRMKLPSPNHSKFFQ 994

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
drl	NP_001260566.1	WIF	21..157	CDD:128745	3/7 (43%)
		PTK_Ryk	336..606	CDD:270639	73/282 (26%)
		Pkinase_Tyr	343..599	CDD:285015	72/268 (27%)
si:ch73-383l1.1	XP_021331611.1	Recep_L_domain	54..166	CDD:307256
		Furin-like	183..331	CDD:307072
		Recep_L_domain	357..477	CDD:307256
		GF_recep_IV	501..633	CDD:317276	25/117 (21%)
		TM_ErbB4	631..674	CDD:213053	13/48 (27%)
		PKc_like	699..995	CDD:328722	84/332 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1025
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900