Protein Alignment drl and mst1rb

DIOPT Version :10

• Sequence 1: NP_001260566.1
• Gene: drl / 44355
• FlyBaseID: FBgn0015380
• Length: 645
• Species: Drosophila melanogaster
• Sequence 2: XP_073773053.1
• Gene: mst1rb / 100134855
• ZFINID: ZDB-GENE-071218-3
• Length: 1374
• Species: Danio rerio
• Alignment Length: 741
• Identity: 189/741 - (25%)
• Similarity: 301/741 - (40%)
• Gaps: 190/741 - (25%)

  Fly    11 LLTLIASGQAH-----LNIFLNLHEVLRLIGVSAELYYVREGAINDYALNFAVPVPANISDVTFT 70
            ||..|.||...     ||:...:||      ...|.:|..:|:.......|.||   ||::|...
Zfish   613 LLCKIRSGTIETLFKPLNVTAKVHE------GQVEGHYSIDGSAEMPGFTFVVP---NITEVQPD 668

  Fly    71 W-----QSLVDHPLPY-------------------SINIA--------------TSDTEVLPRPI 97
            :     .:|:....||                   |:::|              |...:|:.|..
Zfish   669 YGPVDGGTLITITGPYLDSGKNRKVTLDGESCPVQSVSVARGNLSSIVCLSQPVTEVKDVVLRVY 733

  Fly    98 LNISRIGDVPV-----EPQTWGIALKCSGTRNAEVTVT-INVEVILDRATNNNTNLIFKRKKI-- 154
            ::.||:....|     .|:...:...||....:.:.:. .|::.:.      .|.:.|:.|:.
Zfish   734 IDKSRVVTTKVFRYKKTPEILAVLPDCSFDSGSRIIIEGRNLDSVY------RTVVYFQPKESHL 792

  Fly   155 -----------------CL-----REEQDSAHEEYD-DDDLDLLQTARKGHGGDIHYVDR----- 191
                             |:     |:|.:.....:| |..|.|.:     |....|...|
Zfish   793 KPVSTECRGKAKPTRMECITPVFPRDETEEGELSFDMDGVLGLWK-----HDFSYHPYGRPIPFE 852

  Fly   192 NDEHV---------VANGHQAPEKQRPVVT-ESPVGRGNSGGSKRDFDPMLR--ENLVPPASG-- 242
            .:.|:         |:..||........:: ...||..:.||...|.:...|  .||..|:.|
Zfish   853 TEGHILRLYPGFDEVSLHHQKLNLVSSCMSITMTVGDVDCGGKVLDNEITCRIPNNLTIPSEGLP 917

  Fly   243 ------------------------------LVTLIVGGILALVLVSTL----------ILIAYCA 267
                                          |..|:.|.:||.:::..|          ..::|.:
Zfish   918 VKVTVNGYTHNVGTVILVSNHYMVGIVLGILAALVTGAVLAFIVLKNLRKQKKASQTENRLSYFS 982

  Fly   268 KGPSKRHPSNGVHLIKTSSFQR-LPTISSTAHNSIYVCPS-TITPTYATLTRPFREYEH------ 324
            ...|:   ||.|.|.....::| ||..|.||.......|. ..|.|..|...|....|:
Zfish   983 HSRSR---SNSVDLSSLVDYRRDLPLTSITAPTGALAFPGLAYTGTLDTTLTPLMPPENISITSF 1044

  Fly   325 EPEEFNRRLQE-----LTVQKCRVRLSCLVQEGNFGRIYRG--TYNDCQEV--LVKTVAQHASQL 380
            .||    .|:|     :.....:|....::.:|:||.:|.|  |.::.:|:  .||::.:.....
Zfish  1045 RPE----LLEEVKDVLIPASTLKVHHHQIIGKGHFGTVYHGYLTDHNNREIHCAVKSLNRITDVE 1105

  Fly   381 QVNLLLQESMMLYEASHPNVLSVLGISIEDYATPFVL--YAATGSVRNLKSFLQDPSYARSVTTI 443
            :|...|:|.:::....|.||||:|||.:.:...|.|:  |...|.:|:   |::..:  |:.|..
Zfish  1106 EVEQFLKEGILMKGFHHSNVLSLLGILLPEEGLPLVVLPYMKHGDLRH---FIRCEN--RNPTVK 1165

  Fly   444 QTVLMGSQLAMAMEHLHNHGVIHKDIAARNCVIDDQLRVKLTDSALSRDLFPGDYNSLGDGEYR- 507
            ..:..|.|:|..||:|.....:|:|:|||||::|:...||:.|..::||:...:|.|:.|  :|
Zfish  1166 DLIGFGLQVAKGMEYLAQKKFVHRDLAARNCMLDESYTVKVADFGMARDVLEKEYYSVQD--HRK 1228

  Fly   508 ---PIKWLSLEALQKSHYNEGSDVWSFGVLMWEMCTLGKLPYAEIDPYEMEHYLKDGYRLAQPFN 569
               |:||:::|:||...:...|||||||||||||.|.|..||.|:|||::.|:|..|.||.||..
Zfish  1229 AKLPVKWMAIESLQTQKFTTKSDVWSFGVLMWEMLTRGASPYPEVDPYDVTHFLLKGRRLPQPQY 1293

  Fly   570 CPDELFTIMAYCWASMPAERPSFSQL 595
            |||.||.|:..||...|.:|||||.|
Zfish  1294 CPDPLFAILLQCWDPDPEKRPSFSTL 1319

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
drl	NP_001260566.1	WIF	21..157	CDD:128745	32/208 (15%)
		PTK_Ryk	336..606	CDD:270639	101/270 (37%)
mst1rb	XP_073773053.1	None