Protein Alignment drl and mst1ra

DIOPT Version :10

• Sequence 1: NP_001260566.1
• Gene: drl / 44355
• FlyBaseID: FBgn0015380
• Length: 645
• Species: Drosophila melanogaster
• Sequence 2: XP_005166175.1
• Gene: mst1ra / 100002448
• ZFINID: ZDB-GENE-071218-2
• Length: 1356
• Species: Danio rerio
• Alignment Length: 740
• Identity: 184/740 - (24%)
• Similarity: 310/740 - (41%)
• Gaps: 153/740 - (20%)

  Fly     1 MAPNLLTIGLLLTLIASGQAHLNIFLNLHEVLRLIGVSAELYYVREGAINDYALNFAVPVPANIS 65
            :.|...:..||:..|...::.|:..:|:  .:::....|...|...|.......:|..|   .|:
Zfish   599 VVPEKTSSSLLVCRIVGEESGLHQSVNI--TIQVNEKKAGSGYFISGKAGIQGFSFVTP---EIT 658

  Fly    66 DVTFTWQSLVDHPLPYSINIATSDTEVLPRPILNISRIGD--VPVEP-QTWGIALKCSGTRNAEV 127
            |::.::...:...|     |..|...:.......|| :||  .|||. .:.|.::.|. :...:.
Zfish   659 DISPSFGPKIGGTL-----ITLSGKHLDAGGSRTIS-LGDRNCPVESVSSDGTSIVCR-SEGVKD 716

  Fly   128 TVTINVEVILDRATNNNT----------------NLIFKR--KKICLREEQDSAHE---EYDDDD 171
            |:.::|:|::|.:|.::|                |..|:|  |.|...:..||..:   :|....
Zfish   717 TLEVDVKVVIDGSTISSTKTFSYRVNPEVTGVNPNCGFRRGSKIIITGQNLDSVSQAVIKYKGGY 781

  Fly   172 LDLLQTARKGHGG---------------DIHYVDRNDEHVV--------ANGHQAPEKQRPVVTE 213
            .|.::|...|.|.               .|..||.:....:        |||...|.:....|.|
Zfish   782 KDPVETVCSGQGNPTQMECMSPVCEESTGILSVDLDGAKDLQSQTFTCHANGEPIPFETEDRVLE 846

  Fly   214 SPVGRG---------------------------NSGGSKRDFDPMLRENLVPPASG-----LV-- 244
            ...|:.                           |:.....:....:.:||..|..|     ||
Zfish   847 LSPGQDEVSLHHKKLALVSGCMEIIMTVNGVDCNAKVLDNEITCRIPKNLTIPRQGAPVKVLVNR 911

  Fly   245 -------------TLIVG---GILALVLVSTLILIAYCAKGPSKRHPS-----NGVHLIKTS--S 286
                         .||||   ||||.|.|...|:....|:...|:..:     ..:|..:|:  :
Zfish   912 EEHDIGMVVMKNSNLIVGVVLGILAAVGVGAAIVYVAMAQERKKKKAALVEVRLSMHSNRTTAEN 976

  Fly   287 FQRLP-------TI------------SSTAHNSIYVCPSTITPTYATLTRPFREYEHEP---EEF 329
            :.|.|       |:            |.|...|:....|..:.....:.|........|   ||.
Zfish   977 YDRSPDGDYRRETVRPAGLSVSPFHGSGTTFTSLPYAGSMDSAAAPLMRRQVSMSALRPDLLEEV 1041

  Fly   330 NRRLQELTVQKCRVRLSCLVQEGNFGRIYRG--TYNDCQEV--LVKTVAQHASQLQVNLLLQESM 390
            ...|  ::..|.:::...::.:|:||.:|.|  |.:|.:|.  .||::.:.....:|...|:|.:
Zfish  1042 KNVL--ISPDKIKIQHEQIIGKGHFGTVYHGYLTDSDNKETHCAVKSLNRITDLEEVEQFLREGL 1104

  Fly   391 MLYEASHPNVLSVLGISIEDYATPFVL--YAATGSVRNLKSFLQDPSYARSVTTIQTVLMGSQLA 453
            .:....|.:|||:|||.:.....|.|:  |...|.:|:   |::.|.  ||.|....:..|.|:|
Zfish  1105 FMKAFHHSHVLSLLGIVLPSDGLPLVILPYMKHGDLRH---FIRSPE--RSPTVKDLIGFGLQVA 1164

  Fly   454 MAMEHLHNHGVIHKDIAARNCVIDDQLRVKLTDSALSRDLFPGDYNSLGDGEYR--PIKWLSLEA 516
            ..||:|.|...:|:|:|||||::|:...||:.|..::||::..:|.|:.|.:..  |:||::||:
Zfish  1165 KGMEYLANKKFVHRDLAARNCMLDESFTVKVADFGMARDVYDKEYYSIQDSKKAKLPVKWMALES 1229

  Fly   517 LQKSHYNEGSDVWSFGVLMWEMCTLGKLPYAEIDPYEMEHYLKDGYRLAQPFNCPDELFTIMAYC 581
            ||...:...|||||:||||||:.|.|..||.::|||::..||..|.||.||..|.|.|::::..|
Zfish  1230 LQTQKFTTKSDVWSYGVLMWELLTRGASPYPDVDPYDITPYLMQGRRLPQPQYCFDSLWSVLMQC 1294

  Fly   582 WASMPAERPSFSQLQICLSEFHTQI 606
            |...|.:||.|:.|...:.:.|:.:
Zfish  1295 WHPEPEKRPGFTTLVQAVQDIHSSL 1319

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
drl	NP_001260566.1	WIF	21..157	CDD:128745	32/156 (21%)
		PTK_Ryk	336..606	CDD:270639	97/277 (35%)
mst1ra	XP_005166175.1	Sema_MET_like	41..504	CDD:200509
		PSI	507..549	CDD:396154
		IPT	550..654	CDD:472823	10/56 (18%)
		IPT_plexin_repeat2	655..740	CDD:238584	21/94 (22%)
		IPT	742..828	CDD:214657	15/85 (18%)
		PTKc_Met_Ron	1057..1318	CDD:270649	96/265 (36%)