Protein Alignment Shark and HT1

DIOPT Version :10

• Sequence 1: NP_524743.2
• Gene: Shark / 44353
• FlyBaseID: FBgn0015295
• Length: 939
• Species: Drosophila melanogaster
• Sequence 2: NP_176430.2
• Gene: HT1 / 842538
• AraportID: AT1G62400
• Length: 390
• Species: Arabidopsis thaliana
• Alignment Length: 314
• Identity: 85/314 - (27%)
• Similarity: 138/314 - (43%)
• Gaps: 48/314 - (15%)

  Fly   640 PSTPSAT------EVEAAKLRFF--IEPEKLVLDR------EIGHGEFGSVHSGW--------LL 682
            |..||::      |.|..:.:.|  :|...::|:.      |...||    ...|        :.
plant    29 PCNPSSSKTNRYAEAETMEKKRFDSMESWSMILESENVETWEASKGE----REEWTADLSQLFIG 89

  Fly   683 RKSGAGEESRL--------EVAIKML-----SDEHSNK--QEFLREASVMMRLEHKCIVRLIGIA 732
            .|..:|..||:        .||:||:     .:|...|  |:|..|.:::.||.|..||:.|...
plant    90 NKFASGAHSRIYRGIYKQRAVAVKMVRIPTHKEETRAKLEQQFKSEVALLSRLFHPNIVQFIAAC 154

  Fly   733 -KGEMLMMVQELAPLGSMLQYI-LDHGHEITANAELKVWASQIACGMHYLESQHFVHRDLAARNI 795
             |..:..::.|....|::..|: ....:.::....|:: |..|:.||.||.||..:||||.:.|:
plant   155 KKPPVYCIITEYMSQGNLRMYLNKKEPYSLSIETVLRL-ALDISRGMEYLHSQGVIHRDLKSNNL 218

  Fly   796 LLTARHQAKISDFGMSRSLRPGSTEYQFTQGGRWPIRWYAPESFNLGIFSHASDVWSFGVTIWEM 860
            ||....:.|::|||.|..    .|:.:..:|.....||.|||......::...||:|||:.:||:
plant   219 LLNDEMRVKVADFGTSCL----ETQCREAKGNMGTYRWMAPEMIKEKPYTRKVDVYSFGIVLWEL 279

  Fly   861 FSLGAPPYGEISNVDAIKLVDSGERLPQPNLCPAYIYAVMQSCWKERPKDRPTF 914
            .:...|..|......|..:.:..||.|.|..|...:..:::.||.|.|..||.|
plant   280 TTALLPFQGMTPVQAAFAVAEKNERPPLPASCQPALAHLIKRCWSENPSKRPDF 333

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Shark	NP_524743.2	SH2_Nterm_shark_like	8..91	CDD:198210
		ANKYR	<94..317	CDD:440430
		ANK repeat	124..151	CDD:293786
		ANK repeat	153..184	CDD:293786
		ANK repeat	186..217	CDD:293786
		ANK repeat	220..245	CDD:293786
		SH2_Cterm_shark_like	287..395	CDD:198211
		PTKc_Syk_like	666..926	CDD:270650	77/280 (28%)
HT1	NP_176430.2	STKc_MAP3K-like	93..340	CDD:270901	72/246 (29%)