DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Shark and AT5G58950

DIOPT Version :9

Sequence 1:	NP_524743.2	Gene:	Shark / 44353	FlyBaseID:	FBgn0015295	Length:	939	Species:	Drosophila melanogaster
Sequence 2:	NP_568893.1	Gene:	AT5G58950 / 836012	AraportID:	AT5G58950	Length:	525	Species:	Arabidopsis thaliana

Alignment Length:	499	Identity:	119/499 - (23%)
Similarity:	212/499 - (42%)	Gaps:	97/499 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   469 RLTSPKKA----LFDMNSLRKNKSKGKRSDSESSVSGSLAGTEQELQAAAPMLKSLSFSTEFSTF 529
            ||.|.|.|    :.:.:.....|:..:||.|.||.|.|           .|.|.|.:..|...|.
plant    21 RLNSSKLASLPFMINQDKFSGLKAIPQRSSSSSSASSS-----------DPKLVSSNSQTTGDTS 74

  Fly   530 NADGVTGSGAAAAGEVYNV------------PRNNTPI-EIDLPPIAQKTEAEVEYF-TKSDVAI 580
            :.:         |.:||.|            .|:.:|. ::.:|.:.::..:|.:.| |.....:
plant    75 SLE---------AADVYVVDSEIQTNPVTHKQRSVSPSPQMAVPDVFKEARSERKRFSTPHPRRV 130

  Fly   581 ERERAGQWIGNGYQPTMDVLSLLDQQ---IKAPA--VARLNSLGPNASTESEMASYLHRKCSGTP 640
            |.|:       |.:|.:...:..|::   :::|:  :..|.:|......:|:..:...:....|.
plant   131 ESEK-------GMKPKLSHKNSFDKRSFNLRSPSGPIRDLGTLRIQERVKSKKDTGWSKLFDNTG 188

  Fly   641 STPSATEVEAAKLRFFIEPEKLVLDREIGHGEFGSVHSGWLLRKSGAGEESRLEVAIKMLS--DE 703
            ...||.|   |...|.::..||....:..||.:..::.|....|:         ||:|:::  |:
plant   189 RRVSAVE---ASEEFRVDMSKLFFGLKFAHGLYSRLYHGKYEDKA---------VAVKLITVPDD 241

  Fly   704 HSN-------KQEFLREASVMMRLEHKCIVRLIGIAKG-EMLMMVQELAPLGSMLQYILDHGHEI 760
            ..|       :::|.:|.:::.||.|..:::.:|..|. .:..::.:..|.||:..::....:..
plant   242 DDNGCLGARLEKQFTKEVTLLSRLTHPNVIKFVGAYKDPPVYCVLTQYLPEGSLRSFLHKPENRS 306

  Fly   761 TANAELKVWASQIACGMHYLESQHFVHRDLAARNILLTARHQAKISDFGMSRSLR--------PG 817
            ....:|..:|..||.||.|:.|:..:||||...|:|:......||:|||::....        ||
plant   307 LPLKKLIEFAIDIARGMEYIHSRRIIHRDLKPENVLIDEEFHLKIADFGIACEEEYCDMLADDPG 371

  Fly   818 STEYQFTQGGRWPIRWYAPESFNLGIFSHASDVWSFGVTIWEMFSLGAPPYGEISNVD-AIKLVD 881
            :            .||.|||..........:||:|||:.:|||.: ||.||.:::.:. |..:|.
plant   372 T------------YRWMAPEMIKRKPHGRKADVYSFGLVLWEMVA-GAIPYEDMNPIQAAFAVVH 423

  Fly   882 SGERLPQPNLCPAYIYAVMQSCWKERPKDRPTF---VYLTEFFA 922
            ...|...|..||..:.|:::.||...|..||.|   |.:.|.||
plant   424 KNIRPAIPGDCPVAMKALIEQCWSVAPDKRPEFWQIVKVLEQFA 467

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Shark	NP_524743.2	SH2_Nterm_shark_like	8..91	CDD:198210
		Ank_2	<112..184	CDD:289560
		ANK	117..241	CDD:238125
		ANK repeat	124..151	CDD:293786
		ANK repeat	153..184	CDD:293786
		Ank_2	158..247	CDD:289560
		ANK repeat	186..217	CDD:293786
		ANK repeat	220..245	CDD:293786
		Ank_4	224..274	CDD:290365
		SH2_Cterm_shark_like	287..395	CDD:198211
		TyrKc	662..921	CDD:197581	73/280 (26%)
		PTKc_Syk_like	666..926	CDD:270650	74/279 (27%)
AT5G58950	NP_568893.1	STKc_MAP3K-like	214..463	CDD:270901	71/270 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	148	1.000	Inparanoid score	I1725
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.050