DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Shark and AT5G40540

DIOPT Version :9

Sequence 1:	NP_524743.2	Gene:	Shark / 44353	FlyBaseID:	FBgn0015295	Length:	939	Species:	Drosophila melanogaster
Sequence 2:	NP_198870.1	Gene:	AT5G40540 / 834052	AraportID:	AT5G40540	Length:	353	Species:	Arabidopsis thaliana

Alignment Length:	297	Identity:	83/297 - (27%)
Similarity:	146/297 - (49%)	Gaps:	35/297 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   645 ATEVEAAKLRFFIEPEKLVLDREIGHGEFGSVHSGWLLRKSGAGEESRLEVAIKML----SDEHS 705
            :.||.....::.::|:.|.:..:||.|....::.|....|:         ||||::    |.|..
plant     9 SNEVFELDPKWVVDPQHLFVGPKIGEGAHAKIYEGKYKNKT---------VAIKIVKRGESPEEI 64

  Fly   706 NKQE--FLREASVMMRLEHKCIVRLIGIAKGEMLMMVQELAPLGSMLQYILDHGHEITANAELKV 768
            .|:|  |.||.|::.|::||.:|:.||..|..::::|.||...|::.:|::...   ..:.:::|
plant    65 AKRESRFAREVSMLSRVQHKNLVKFIGACKEPIMVIVTELLLGGTLRKYLVSLR---PGSLDIRV 126

  Fly   769 ---WASQIACGMHYLESQHFVHRDLAARNILLTARHQ-AKISDFGMSRSLRPGSTEYQFTQGGRW 829
               :|..||..|..|.|...:||||...:::|||.:: .|::|||::|  ....||....:.|.:
plant   127 AVGYALDIARAMECLHSHGVIHRDLKPESLILTADYKTVKLADFGLAR--EESLTEMMTAETGTY 189

  Fly   830 PIRWYAPESFNLGI--------FSHASDVWSFGVTIWEMFSLGAPPYGEISNVDAIKLVDSGERL 886
              ||.|||.::...        ::|..|.:||.:.:||:.. ...|:..:||:.|..........
plant   190 --RWMAPELYSTVTLRHGEKKHYNHKVDAYSFAIVLWELIH-NKLPFEGMSNLQAAYAAAFKNVR 251

  Fly   887 PQPNLCPAYIYAVMQSCWKERPKDRPTFVYLTEFFAR 923
            |..:..|..:..::.|||||.|.|||.|..:.:...|
plant   252 PSADDLPKDLAMIVTSCWKEDPNDRPNFTEIIQMLLR 288

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Shark	NP_524743.2	SH2_Nterm_shark_like	8..91	CDD:198210
		Ank_2	<112..184	CDD:289560
		ANK	117..241	CDD:238125
		ANK repeat	124..151	CDD:293786
		ANK repeat	153..184	CDD:293786
		Ank_2	158..247	CDD:289560
		ANK repeat	186..217	CDD:293786
		ANK repeat	220..245	CDD:293786
		Ank_4	224..274	CDD:290365
		SH2_Cterm_shark_like	287..395	CDD:198211
		TyrKc	662..921	CDD:197581	79/276 (29%)
		PTKc_Syk_like	666..926	CDD:270650	79/276 (29%)
AT5G40540	NP_198870.1	STKc_MAP3K-like	32..286	CDD:270901	78/270 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	148	1.000	Inparanoid score	I1725
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	2.050