DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Shark and AT5G01850

DIOPT Version :9

Sequence 1:	NP_524743.2	Gene:	Shark / 44353	FlyBaseID:	FBgn0015295	Length:	939	Species:	Drosophila melanogaster
Sequence 2:	NP_001332324.1	Gene:	AT5G01850 / 831760	AraportID:	AT5G01850	Length:	357	Species:	Arabidopsis thaliana

Alignment Length:	323	Identity:	88/323 - (27%)
Similarity:	150/323 - (46%)	Gaps:	62/323 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   657 IEPEKLVLDREIGHGEFGSVHSGWLLRKSGAGEESRLEVAIKMLS-----DEHSN-KQEFLREAS 715
            ::|:.|.:..:||.|..|.|:.         |...|..||||:::     |:.|: :..|:||.:
plant    13 VDPKLLFIGSKIGEGAHGKVYQ---------GRYGRQIVAIKVVNRGSKPDQQSSLESRFVREVN 68

  Fly   716 VMMRLEHKCIVRL------------------------IGIAKGEMLMMVQELAPLGSMLQYILDH 756
            :|.|::|..:|::                        ||..|..::::|.||.|..|:.:|:...
plant    69 MMSRVQHHNLVKVSLLLSSLSLLSILLLEYTISIWQFIGACKDPLMVIVTELLPGMSLRKYLTSI 133

  Fly   757 GHEITANAELKVWASQIACGMHYLESQHFVHRDLAARNILLTARHQA-KISDFGMSRSLRPGSTE 820
            ..::........:|..||..:|.|.:...:||||...|:|||..|:: |::|||::|  ....||
plant   134 RPQLLHLPLALSFALDIARALHCLHANGIIHRDLKPDNLLLTENHKSVKLADFGLAR--EESVTE 196

  Fly   821 YQFTQGGRWPIRWYAPESFNLGI--------FSHASDVWSFGVTIWEMFSLGAPPYGEISNVDAI 877
            ....:.|.:  ||.|||.::...        :::..||:|||:.:||:.: ...|:..:||:.|.
plant   197 MMTAETGTY--RWMAPELYSTVTLRQGEKKHYNNKVDVYSFGIVLWELLT-NRMPFEGMSNLQAA 258

  Fly   878 KLVDSGERLP--QPNLCPAYIYAVMQSCWKERPKDRPTFV----YLTEFF--ARDPDYQNLPE 932
            ......:..|  ...:.|:..: ::||||.|.|..||:|.    .|.||.  ...|..|.|||
plant   259 YAAAFKQERPVMPEGISPSLAF-IVQSCWVEDPNMRPSFSQIIRLLNEFLLTLTPPPPQPLPE 320

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Shark	NP_524743.2	SH2_Nterm_shark_like	8..91	CDD:198210
		Ank_2	<112..184	CDD:289560
		ANK	117..241	CDD:238125
		ANK repeat	124..151	CDD:293786
		ANK repeat	153..184	CDD:293786
		Ank_2	158..247	CDD:289560
		ANK repeat	186..217	CDD:293786
		ANK repeat	220..245	CDD:293786
		Ank_4	224..274	CDD:290365
		SH2_Cterm_shark_like	287..395	CDD:198211
		TyrKc	662..921	CDD:197581	81/303 (27%)
		PTKc_Syk_like	666..926	CDD:270650	81/306 (26%)
AT5G01850	NP_001332324.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	148	1.000	Inparanoid score	I1725
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.050