DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Shark and ATN1

DIOPT Version :9

Sequence 1:	NP_524743.2	Gene:	Shark / 44353	FlyBaseID:	FBgn0015295	Length:	939	Species:	Drosophila melanogaster
Sequence 2:	NP_189393.1	Gene:	ATN1 / 822378	AraportID:	AT3G27560	Length:	356	Species:	Arabidopsis thaliana

Alignment Length:	297	Identity:	82/297 - (27%)
Similarity:	146/297 - (49%)	Gaps:	31/297 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   654 RFFIEPEKLVLDREIGHGEFGSVHSGWLLRKSGAGEESRLEVAIKML----SDEHSNKQE--FLR 712
            ::.::|..|.:..:||.|....|:.|....::         ||||::    |.|...|::  |.|
plant    18 KWLVDPRHLFVGPKIGEGAHAKVYEGKYRNQT---------VAIKIIKRGESPEEIAKRDNRFAR 73

  Fly   713 EASVMMRLEHKCIVRLIGIAKGEMLMMVQELAPLGSMLQYILDHGHEITANAELKV-WASQIACG 776
            |.:::.:::||.:|:.||..|..|:::|.||...|::.:|::....: ..:..|.| :|..||..
plant    74 EIAMLSKVQHKNLVKFIGACKEPMMVIVTELLLGGTLRKYLVSLRPK-RLDIRLAVGFALDIARA 137

  Fly   777 MHYLESQHFVHRDLAARNILLTARHQ-AKISDFGMSRSLRPGSTEYQFTQGGRWPIRWYAPESFN 840
            |..|.|...:||||...|::|:|.|: .|::|||::|  ....||....:.|.:  ||.|||.::
plant   138 MECLHSHGIIHRDLKPENLILSADHKTVKLADFGLAR--EESLTEMMTAETGTY--RWMAPELYS 198

  Fly   841 LGI--------FSHASDVWSFGVTIWEMFSLGAPPYGEISNVDAIKLVDSGERLPQPNLCPAYIY 897
            ...        ::|..|.:||.:.:||:. |...|:..:||:.|..........|.....|..:.
plant   199 TVTLRQGEKKHYNHKVDAYSFAIVLWELI-LNKLPFEGMSNLQAAYAAAFKNLRPSAEDLPGDLE 262

  Fly   898 AVMQSCWKERPKDRPTFVYLTEFFARDPDYQNLPELV 934
            .::.|||||.|.:||.|..:.:...|.....:.|:::
plant   263 MIVTSCWKEDPNERPNFTEIIQMLLRYLTTVSAPQII 299

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Shark	NP_524743.2	SH2_Nterm_shark_like	8..91	CDD:198210
		Ank_2	<112..184	CDD:289560
		ANK	117..241	CDD:238125
		ANK repeat	124..151	CDD:293786
		ANK repeat	153..184	CDD:293786
		Ank_2	158..247	CDD:289560
		ANK repeat	186..217	CDD:293786
		ANK repeat	220..245	CDD:293786
		Ank_4	224..274	CDD:290365
		SH2_Cterm_shark_like	287..395	CDD:198211
		TyrKc	662..921	CDD:197581	79/274 (29%)
		PTKc_Syk_like	666..926	CDD:270650	79/275 (29%)
ATN1	NP_189393.1	STKc_MAP3K-like	32..286	CDD:270901	78/268 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	148	1.000	Inparanoid score	I1725
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	2.050