DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Shark and AT2G24360

DIOPT Version :9

Sequence 1:	NP_524743.2	Gene:	Shark / 44353	FlyBaseID:	FBgn0015295	Length:	939	Species:	Drosophila melanogaster
Sequence 2:	NP_565568.1	Gene:	AT2G24360 / 816972	AraportID:	AT2G24360	Length:	411	Species:	Arabidopsis thaliana

Alignment Length:	271	Identity:	86/271 - (31%)
Similarity:	138/271 - (50%)	Gaps:	29/271 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   657 IEPEKLVLDREIGHGEFGSVHSGWLLRKSGAGEESRLEVAIKMLSDEHSN-------KQEFLREA 714
            |:..||.:......|.||.::.|     :..||    :||||:|....::       :|:|.:|.
plant   125 IDLRKLNMGPAFAQGAFGKLYKG-----TYNGE----DVAIKILERPENSPEKAQFMEQQFQQEV 180

  Fly   715 SVMMRLEHKCIVRLIGIAKGEML-MMVQELAPLGSMLQYILDHGHEITANAELKVWASQ---IAC 775
            |::..|:|..|||.||..:..|: .:|.|.|..||:.|::....:..   ..||:...|   :|.
plant   181 SMLANLKHPNIVRFIGACRKPMVWCIVTEYAKGGSVRQFLTRRQNRA---VPLKLAVKQALDVAR 242

  Fly   776 GMHYLESQHFVHRDLAARNILLTARHQAKISDFGMSRSLRPGSTEYQFTQGGRWPIRWYAPESFN 840
            ||.|:..::|:||||.:.|:|::|....||:|||::|.  ...||....:.|.:  ||.|||...
plant   243 GMAYVHGRNFIHRDLKSDNLLISADKSIKIADFGVARI--EVQTEGMTPETGTY--RWMAPEMIQ 303

  Fly   841 LGIFSHASDVWSFGVTIWEMFSLGAPPYGEISNVD-AIKLVDSGERLPQPNLCPAYIYAVMQSCW 904
            ...::...||:|||:.:||:.: |..|:..::.|. |..:|:.|.|...||.|...:..:|..||
plant   304 HRAYNQKVDVYSFGIVLWELIT-GLLPFQNMTAVQAAFAVVNRGVRPTVPNDCLPVLSDIMTRCW 367

  Fly   905 KERPKDRPTFV 915
            ...|:.||.||
plant   368 DANPEVRPCFV 378

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Shark	NP_524743.2	SH2_Nterm_shark_like	8..91	CDD:198210
		Ank_2	<112..184	CDD:289560
		ANK	117..241	CDD:238125
		ANK repeat	124..151	CDD:293786
		ANK repeat	153..184	CDD:293786
		Ank_2	158..247	CDD:289560
		ANK repeat	186..217	CDD:293786
		ANK repeat	220..245	CDD:293786
		Ank_4	224..274	CDD:290365
		SH2_Cterm_shark_like	287..395	CDD:198211
		TyrKc	662..921	CDD:197581	84/266 (32%)
		PTKc_Syk_like	666..926	CDD:270650	83/262 (32%)
AT2G24360	NP_565568.1	STKc_MAP3K-like	137..384	CDD:270901	83/259 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	148	1.000	Inparanoid score	I1725
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.050