| Sequence 1: | NP_524743.2 | Gene: | Shark / 44353 | FlyBaseID: | FBgn0015295 | Length: | 939 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_001372133.1 | Gene: | TYK2 / 7297 | HGNCID: | 12440 | Length: | 1257 | Species: | Homo sapiens |
| Alignment Length: | 294 | Identity: | 103/294 - (35%) |
|---|---|---|---|
| Similarity: | 160/294 - (54%) | Gaps: | 42/294 - (14%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 666 REIGHGEFGSVHSGWLL--RKSGAGEESRLEVAIKMLSDE--HSNKQEFLREASVMMRLEHKCIV 726
Fly 727 RLIGIA--KGE-MLMMVQELAPLGSMLQYILDHGHEITANAELKVWASQIACGMHYLESQHFVHR 788
Fly 789 DLAARNILLTARHQAKISDFGMSRSLRPGSTEYQFTQGGRWPIRWYAPESFNLGIFSHASDVWSF 853
Fly 854 GVTIWEMF----SLGAPP----------YGEISNVDAIKLVDSGERLPQPNLCPAYIYAVMQSCW 904
Fly 905 KERPKDRPTFVYLTEFFARDPDYQNLPELVQTVH 938 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Shark | NP_524743.2 | SH2_Nterm_shark_like | 8..91 | CDD:198210 | |
| Ank_2 | <112..184 | CDD:289560 | |||
| ANK | 117..241 | CDD:238125 | |||
| ANK repeat | 124..151 | CDD:293786 | |||
| ANK repeat | 153..184 | CDD:293786 | |||
| Ank_2 | 158..247 | CDD:289560 | |||
| ANK repeat | 186..217 | CDD:293786 | |||
| ANK repeat | 220..245 | CDD:293786 | |||
| Ank_4 | 224..274 | CDD:290365 | |||
| SH2_Cterm_shark_like | 287..395 | CDD:198211 | |||
| TyrKc | 662..921 | CDD:197581 | 98/275 (36%) | ||
| PTKc_Syk_like | 666..926 | CDD:270650 | 98/280 (35%) | ||
| TYK2 | NP_001372133.1 | FERM_F1 | 28..125 | CDD:408179 | |
| FERM_F2 | 143..266 | CDD:408177 | |||
| Jak1_Phl | 285..432 | CDD:407742 | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 335..366 | ||||
| SH2 | 437..534 | CDD:417686 | |||
| PKc_like | 589..937 | CDD:419665 | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 610..629 | ||||
| PTKc_Tyk2_rpt2 | 962..1244 | CDD:270664 | 103/294 (35%) | ||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E2759_KOG0197 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 0 | 0.000 | Not matched by this tool. | |||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 1 | 0.900 | |||||