Protein Alignment Shark and src

DIOPT Version :9

• Sequence 1: NP_524743.2
• Gene: Shark / 44353
• FlyBaseID: FBgn0015295
• Length: 939
• Species: Drosophila melanogaster
• Sequence 2: XP_017953215.1
• Gene: src / 496893
• XenbaseID: XB-GENE-489820
• Length: 544
• Species: Xenopus tropicalis
• Alignment Length: 571
• Identity: 149/571 - (26%)
• Similarity: 246/571 - (43%)
• Gaps: 106/571 - (18%)

  Fly   423 KPKAASPATPPTPVSPHSHH-----QHPHVPALTITKKKQKE---------------NSSSMFNT 467
            ||:...|.:....::..||.     .....|:.::...:|..               |.|.
 Frog    10 KPREGGPRSRSLDIAEGSHQPFTSLSASQTPSKSLDSHRQPAQPFGGNCDLTPFGGVNFSD---- 70

  Fly   468 LRLTSPKK------------ALFDMNSLRKNKSKGKRSDSESSVSGSLAGTEQELQAAAPML-KS 519
             .:|||::            ||:|..|..:.....|:.:....|:    .|..:::.....| :|
 Frog    71 -TITSPQRIGPLAGGVTTFVALYDYESRTETDLSFKKGERLQIVN----NTRPDMREGDWWLARS 130

  Fly   520 LSFSTEFSTFNADGVTGSGAAAAGEVYNVPRNNTPIEIDLPPIAQKTEAEVEYFTKSDVAIERER 584
            || |.:.....::.|..|.:..|.|.|               :.:.|..|.|...   :::|..|
 Frog   131 LS-SGQTGYIPSNYVAPSDSIQAEEWY---------------LGKITRREAERLL---LSLENPR 176

  Fly   585 AGQWIGNGYQPTMDV--LSLLDQ------QIKAPAVARLNSLGPNASTESEMAS----------- 630
             |.::....:.|...  ||:.|.      .:|...:.:|:|.|...::.::.:|
 Frog   177 -GTFLVRESETTKGAYCLSVSDYDANRGLNVKHYKIRKLDSGGFYITSRTQFSSLQQLVAYYSKH 240

  Fly   631 ---YLHRKCSGTPSTPSATEVEAAKLRFFIEPEKLVLDREIGHGEFGSVHSG-----WLLRKSGA 687
               ..||..:..|:....|: ..:|..:.|..:.|.|:.::|.|.||.|..|     |
 Frog   241 ADGLCHRLTTVCPTAKPQTQ-GLSKDAWEIPRDSLRLELKLGQGCFGEVWMGVSVGTW------- 297

  Fly   688 GEESRLEVAIKMLSDEHSNKQEFLREASVMMRLEHKCIVRLIGIAKGEMLMMVQELAPLGSMLQY 752
              .....||||.|.....:.:.||:||.||.:|.|:.:|:|..:...|.:.:|.|....||:|.:
 Frog   298 --NGTTRVAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSEEPIYIVTEYMSKGSLLDF 360

  Fly   753 ILDHGHEITANAELKVWASQIACGMHYLESQHFVHRDLAARNILLTARHQAKISDFGMSRSLRPG 817
            :...........:|...|:|||.||.|:|..::|||||.|.|||:......|::|||::|.:.
 Frog   361 LKGEMGRYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIE-- 423

  Fly   818 STEYQFTQGGRWPIRWYAPESFNLGIFSHASDVWSFGVTIWEMFSLGAPPYGEISNVDAIKLVDS 882
            ..||...||.::||:|.|||:...|.|:..|||||||:.:.|:.:.|..||..:.|.:.:..|:.
 Frog   424 DNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVER 488

  Fly   883 GERLPQPNLCPAYIYAVMQSCWKERPKDRPTFVYLTEFF-----ARDPDYQ 928
            |.|:|.|..||..::.:|..||::.|::||||.||..|.     |.:|.||
 Frog   489 GYRMPCPPDCPESLHDLMCQCWRKDPEERPTFEYLQAFLEDYFTATEPQYQ 539

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Shark	NP_524743.2	SH2_Nterm_shark_like	8..91	CDD:198210
		Ank_2	<112..184	CDD:289560
		ANK	117..241	CDD:238125
		ANK repeat	124..151	CDD:293786
		ANK repeat	153..184	CDD:293786
		Ank_2	158..247	CDD:289560
		ANK repeat	186..217	CDD:293786
		ANK repeat	220..245	CDD:293786
		Ank_4	224..274	CDD:290365
		SH2_Cterm_shark_like	287..395	CDD:198211
		TyrKc	662..921	CDD:197581	94/263 (36%)
		PTKc_Syk_like	666..926	CDD:270650	94/269 (35%)
src	XP_017953215.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000