Protein Alignment Shark and kin-26

DIOPT Version :10

• Sequence 1: NP_524743.2
• Gene: Shark / 44353
• FlyBaseID: FBgn0015295
• Length: 939
• Species: Drosophila melanogaster
• Sequence 2: NP_501309.1
• Gene: kin-26 / 177575
• WormBaseID: WBGene00002208
• Length: 433
• Species: Caenorhabditis elegans
• Alignment Length: 271
• Identity: 91/271 - (33%)
• Similarity: 143/271 - (52%)
• Gaps: 14/271 - (5%)

  Fly   657 IEPEKLVLDREIGHGEFGSVHSGWLLRKSGAGEESRLEVAIKMLSDEHSNK---QEFLREASVMM 718
            :|.:::.:.:::|.|.||.|.||.:..|.|.   ..::||||.:..:.:.|   ::||.||..|.
 Worm   125 LEHDQITIHKKLGEGAFGEVSSGVMKFKKGM---KTVQVAIKQVKLDKTGKAKIKDFLAEARTMR 186

  Fly   719 RLEHKCIVRLIGI-AKGEMLMMVQELAPLGSMLQYILDHGHEITANAELKVWASQIACGMHYLES 782
            :|.|:.|::..|: ...|.|.:|.|||..|: |...|....:::.:.:.:: ..|.|.|:.|:..
 Worm   187 KLGHQNIIKFYGVGVLQEPLYLVMELAVNGA-LDSFLKKNEDLSVDKKTEM-ILQAAWGLEYIHG 249

  Fly   783 QHFVHRDLAARNILLTARHQAKISDFGMSRSLRPGSTEYQFTQGGRWPIRWYAPESFNLGIFSHA 847
            :..:|||:||||.|.| ..:.||||||::|:    .|.||.....:.||||.|.|:....|.|..
 Worm   250 KPMLHRDIAARNCLYT-DGKVKISDFGLTRN----GTVYQIKPNTKSPIRWLAIETIKTMICSEK 309

  Fly   848 SDVWSFGVTIWEMFSLGAPPYGEISNVDAIKLVDSGERLPQPNLCPAYIYAVMQSCWKERPKDRP 912
            :|||::||..||:|:..|.||..:...|....|.:|.|:|......|.|..:|..|..|.|.|||
 Worm   310 TDVWAYGVLCWEIFNNAAEPYPGMKPADVATQVANGYRMPPYPHAQAEIQTMMARCNAENPNDRP 374

  Fly   913 TFVYLTEFFAR 923
            :...:.|...|
 Worm   375 SMAEIAEILQR 385

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Shark	NP_524743.2	SH2_Nterm_shark_like	8..91	CDD:198210
		ANKYR	<94..317	CDD:440430
		ANK repeat	124..151	CDD:293786
		ANK repeat	153..184	CDD:293786
		ANK repeat	186..217	CDD:293786
		ANK repeat	220..245	CDD:293786
		SH2_Cterm_shark_like	287..395	CDD:198211
		PTKc_Syk_like	666..926	CDD:270650	90/262 (34%)
kin-26	NP_501309.1	SH2_Fps_family	15..108	CDD:198224
		TyrKc	130..383	CDD:197581	89/262 (34%)