Protein Alignment Shark and styk1

DIOPT Version :10

• Sequence 1: NP_524743.2
• Gene: Shark / 44353
• FlyBaseID: FBgn0015295
• Length: 939
• Species: Drosophila melanogaster
• Sequence 2: NP_001123790.1
• Gene: styk1 / 100170540
• XenbaseID: XB-GENE-979179
• Length: 419
• Species: Xenopus tropicalis
• Alignment Length: 307
• Identity: 89/307 - (28%)
• Similarity: 145/307 - (47%)
• Gaps: 47/307 - (15%)

  Fly   643 PS--ATEVEAAKLRFFIEPEKLVLDREIGHGEFGSVHSGWLLRKSGAGEESRLEVAIKMLSDEHS 705
            ||  |.|:...::|   :|.:|.     |.|.||.::.   .:.:|..:....:|.||.|.:...
 Frog    98 PSLQALEIPRGRIR---QPLQLA-----GEGRFGPIYR---TKLNGPEDGKEKDVIIKRLRNSCG 151

  Fly   706 NKQ--EFLREASVMMRL-EHKCIVRLIGIAKGE--MLMMVQELAPLGSMLQYILDHGHEITAN-- 763
            .::  :||:..:....| :|..||.|:|....|  ..|:::.:.| ||:|.::.|...::.:.
 Frog   152 AQEIRDFLQRVAFQGWLGQHPNIVELLGCCPNEKPFCMVLENIEP-GSLLHFLWDCRRDVMSMDG 215

  Fly   764 -----AELKVW--ASQIACGMHYLESQHFVHRDLAARNILLTARHQAKISDFGMSRSLRPGSTEY 821
                 .|.:|:  |.|:...:.:|..:...|.||||||||:.....||::..|.:..:|...|
 Frog   216 ILYDLTECQVYTIALQVLSALGFLHQRKLFHGDLAARNILIHRNLTAKLTGLGGACEMRQTGT-- 278

  Fly   822 QFTQGGRWPIRWYAPESFNLGIFSHASDVWSFGVTIWEMFSLGAPPYGEISNVDAIKLVDSGERL 886
             |......|::|.|||.......|..|||||||:.::||.:||||||.||...|.::.:..|..:
 Frog   279 -FPSRRPAPLKWMAPERLLRLPISAKSDVWSFGILLYEMITLGAPPYPEIPPNDILQHLQRGNIM 342

  Fly   887 PQPNLCPAYIYAVMQSCWKERPKDRPTFVYLTEFFARDPDYQNLPEL 933
            .:|..|...:|.||:.||..:..:||                :||||
 Frog   343 KRPPTCKPAMYNVMKICWLWKAPERP----------------SLPEL 373

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Shark	NP_524743.2	SH2_Nterm_shark_like	8..91	CDD:198210
		ANKYR	<94..317	CDD:440430
		ANK repeat	124..151	CDD:293786
		ANK repeat	153..184	CDD:293786
		ANK repeat	186..217	CDD:293786
		ANK repeat	220..245	CDD:293786
		SH2_Cterm_shark_like	287..395	CDD:198211
		PTKc_Syk_like	666..926	CDD:270650	78/273 (29%)
styk1	NP_001123790.1	PTKc	118..378	CDD:270623	82/279 (29%)