DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CanB and GUCA1C

DIOPT Version :9

Sequence 1:	NP_001245531.1	Gene:	CanB / 44317	FlyBaseID:	FBgn0010014	Length:	170	Species:	Drosophila melanogaster
Sequence 2:	NP_005450.3	Gene:	GUCA1C / 9626	HGNCID:	4680	Length:	209	Species:	Homo sapiens

Alignment Length:	126	Identity:	37/126 - (29%)
Similarity:	66/126 - (52%)	Gaps:	9/126 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 SGALSIDEFMSLPELQ-----QNPLVQRVIDIFDADGNGEVDFKEFIQGVSQFSVRGDKL-SKLR 93
            ||..::.||.:|..||     .|..:.:|.:.||.:.:|.|||.|||..|:  .:..:|: .||:
Human    32 SGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVN--LIMQEKMEQKLK 94

  Fly    94 FAFRIYDMDNDGYISNGELFQVLKMMVGNNLKDT-QLQQIVDKTICFADKDEDGKISFDEF 153
            :.|::||.|.:|.|...||..:...:...|.:.| ..::.::......|.:.||:::.:||
Human    95 WYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELTLEEF 155

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CanB	NP_001245531.1	FRQ1	13..154	CDD:227455	37/126 (29%)
GUCA1C	NP_005450.3	FRQ1	15..165	CDD:227455	37/126 (29%)
		EFh	56..118	CDD:238008	22/63 (35%)
		EFh	92..160	CDD:238008	17/64 (27%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	187..209
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1271942at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.920