DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CanB and CIB1

DIOPT Version :9

Sequence 1:	NP_001245531.1	Gene:	CanB / 44317	FlyBaseID:	FBgn0010014	Length:	170	Species:	Drosophila melanogaster
Sequence 2:	XP_006720438.1	Gene:	CIB1 / 10519	HGNCID:	16920	Length:	264	Species:	Homo sapiens

Alignment Length:	178	Identity:	43/178 - (24%)
Similarity:	87/178 - (48%)	Gaps:	19/178 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 GNETSLPMDMCSNFD------ADEIRRLGKRF--------RKLDLDNSGALSIDEFMSLPELQQN 52
            |:.:.|..::.:.:.      ..||....:||        |.::......:..::.:|||||:.|
Human     3 GSGSRLSKELLAEYQDLTFLTKQEILLAHRRFCELLPQEQRSVESSLRAQVPFEQILSLPELKAN 67

  Fly    53 PLVQRVIDIFD-ADGNGEVDFKEFIQGVSQFSVRGDKLSKLRFAFRIYDMDNDGYISNGELFQVL 116
            |..:|:..:|. :.....:.|::|:..:|.||.......|..:||||:|.|:||.::..:|.:::
Human    68 PFKERICRVFSTSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSRLV 132

  Fly   117 KMMVG----NNLKDTQLQQIVDKTICFADKDEDGKISFDEFCSVVGNT 160
            ..:.|    ..|..::::|::|..:..:|.|.||.|:..||..|:..:
Human   133 NCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVISRS 180

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CanB	NP_001245531.1	FRQ1	13..154	CDD:227455	39/159 (25%)
CIB1	XP_006720438.1	EF-hand_8	82..132	CDD:290545	15/49 (31%)
		EF-hand_7	109..177	CDD:290234	20/67 (30%)
		EFh	111..178	CDD:238008	21/66 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0034
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1271942at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820