DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment pie and Phf7

DIOPT Version :9

Sequence 1:	NP_001260348.1	Gene:	pie / 44315	FlyBaseID:	FBgn0005683	Length:	582	Species:	Drosophila melanogaster
Sequence 2:	NP_082225.1	Gene:	Phf7 / 71838	MGIID:	1919088	Length:	307	Species:	Mus musculus

Alignment Length:	294	Identity:	101/294 - (34%)
Similarity:	155/294 - (52%)	Gaps:	26/294 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 CLICKYSDTDDLVFGEWMIVRNLQVHYFCLLLSTHLPQRGGDSSGILGFLLRDIREEAAAAEKRK 73
            ||:|.....|....||::...||.||||||:||:.|||:|..:.|:.||:..||:.||..|.|:.
Mouse    33 CLLCLQEPGDPEKLGEFLQKDNLCVHYFCLILSSRLPQKGQPNRGLHGFMPEDIKREAVRASKKI 97

  Fly    74 CWYCNKIGASLQC--DRCRSLFHLKCGLENRAVFEFCGQYKSYCYKCRPMDDYKRQLQSNPPRNA 136
            |:.|.|.||:::|  |:|...|||.||.|...:.:|.|:|||||.|.||    .:.:........
Mouse    98 CFVCKKKGAAIRCQNDQCVQNFHLPCGQERGCLSQFFGEYKSYCRKHRP----TQNIHQGSLGEE 158

  Fly   137 TCPICFSSIYKVELHCVVYGDCCRLGFAHKKCMRQYALTSG-YYLRCIWCRS-ERFRDSIRLQSV 199
            :|.:|..::.:..:. .:...||.....|:||:::||.||. ::.:|..|.: |.|...:....:
Mouse   159 SCVLCCENLSRTSVE-NIQSPCCSQAIYHRKCIQKYAHTSAKHFFKCPQCNNREEFPQEMLRMGI 222

  Fly   200 FVPDRDATWEKQRNAYRELHERNLKCDQPNCLCPSGRT--YNRLSWVILCCSSCAATSAHLKCLV 262
            .:|||||.||.:..|:.||::|...||.|.||...||.  .:...|.::.|::|.:...|..|
Mouse   223 HIPDRDAAWELEPGAFSELYQRYRHCDAPICLYEQGRDSFEDEGRWRLILCATCGSHGTHRDC-- 285

  Fly   263 GALRLPKKRERTDFKCSMCLDVERRIAEGPARTT 296
            .:||...|:    ::|:.||         ||.||
Mouse   286 SSLRPNSKK----WECNECL---------PASTT 306

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
pie	NP_001260348.1	PHD_SF	9..117	CDD:304600	50/109 (46%)
		PHD_SF	224..>260	CDD:304600	11/37 (30%)
		PARM	318..>491	CDD:293666
Phf7	NP_082225.1	ePHD_PHF7_G2E3_like	33..144	CDD:277139	50/110 (45%)
Phf7	NP_082225.1	PHD_PHF7_G2E3_like	247..300	CDD:276971	16/58 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167831379
Domainoid	1	1.000	94	1.000	Domainoid score	I7456
eggNOG	1	0.900	-	-		E2759_KOG1084
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S6144
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D110264at33208
OrthoFinder	1	1.000	-	-		FOG0003998
OrthoInspector	1	1.000	-	-		otm43314
orthoMCL	1	0.900	-	-		OOG6_106451
Panther	1	1.100	-	-	O	PTHR12420
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X3283
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	11	10.700