DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment pie and Phf11c

DIOPT Version :9

Sequence 1:	NP_001260348.1	Gene:	pie / 44315	FlyBaseID:	FBgn0005683	Length:	582	Species:	Drosophila melanogaster
Sequence 2:	NP_001157761.1	Gene:	Phf11c / 628705	MGIID:	3648476	Length:	339	Species:	Mus musculus

Alignment Length:	292	Identity:	57/292 - (19%)
Similarity:	94/292 - (32%)	Gaps:	81/292 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 EDNKELQCLICKYSDTDDLVFGEWMIV-----RNLQVHYFCLLLSTHLPQ----------RGGDS 51
            |..::..|.:|....       :|.::     .|:..|..|||.|:.|.:          |..|.
Mouse    41 EKMEKRTCALCPEGH-------DWSVIYFVPSANIAAHENCLLYSSGLVECEAHNPCKIARNVDV 98

  Fly    52 SGILGFLLRDIREEAAAAEKRKCWYCNKIGASLQCDR--CRSLFHLKCGLENRAVFE--FCGQYK 112
            ..:|        |.........|.:||..||.::|..  |...:||.|..|:.||.:  ....||
Mouse    99 KSVL--------ERIWRGSTMICSFCNNEGAIVRCGETSCAKNYHLFCAKEDYAVLQGGVTRTYK 155

  Fly   113 SYCYKCRPMDD----------------YKRQLQSNPPRNATCPICFSSIYKVELHCVVYGDCCRL 161
            .:|.:..|..:                .|::|.|.||..........|...|....:.:.|....
Mouse   156 LFCPEHPPQQEEATESADGPSMKRKRGRKKRLSSGPPAQPKVVKFMRSKRHVTGEPLGHRDAAVK 220

  Fly   162 GFAHKKCMR--------QYALTSGYYLRCIWCR------SER--------------FRDSIRLQS 198
            ....|||.:        :|.|..   :..|:.|      ||.              |:|::|...
Mouse   221 APFLKKCKKAGLLNVLLEYILEK---MNSIYGRLLDETASESDYEGIETLLFGCGLFKDTLRKFQ 282

  Fly   199 VFVPDRDATWEKQRNAYRELHERNLKCDQPNC 230
            ..:..:...||:::...::..|......|..|
Mouse   283 EVIKSKACEWEERQRLMKQQLEALADLQQSLC 314

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
pie	NP_001260348.1	PHD_SF	9..117	CDD:304600	30/126 (24%)
		PHD_SF	224..>260	CDD:304600	2/7 (29%)
		PARM	318..>491	CDD:293666
Phf11c	NP_001157761.1	PHD_SF	48..161	CDD:304600	30/127 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1084
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12420
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	4	3.870