DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment pie and si:ch211-37e10.1

DIOPT Version :9

Sequence 1:	NP_001260348.1	Gene:	pie / 44315	FlyBaseID:	FBgn0005683	Length:	582	Species:	Drosophila melanogaster
Sequence 2:	XP_017209386.2	Gene:	si:ch211-37e10.1 / 567550	ZFINID:	ZDB-GENE-131127-547	Length:	661	Species:	Danio rerio

Alignment Length:	257	Identity:	55/257 - (21%)
Similarity:	80/257 - (31%)	Gaps:	79/257 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   264 ALRLPKKRERTDFKCSMCLDVERR---IAEGPARTTEETNADG----DNQVDGSF---------Y 312
            :||..::::|...:.|..  .|||   |.|...||.||. |||    ....||:.         .
Zfish    63 SLRADQEKDRRTEEISQY--EERRLKIIQERLMRTNEEP-ADGIPLKFTFPDGTMKIRRFQVFDQ 124

  Fly   313 VQKLGPDAATRSLTQTPVFSEEDESERSSNITV---------------------------IFSQP 350
            :|.|.....|.|......:.:|..|..|.:.||                           :|.|.
Zfish   125 IQALFDFVGTHSSATEYFYIKEATSAVSISSTVPGTLLDHYLNAPLNIHVRWMEMEDVQALFHQQ 189

  Fly   351 KSNATSERLSLSPPQEEMIVEIPDSPEASPKTSIDENHSPQPIARRDTSDSPQPIA-----ASEI 410
            .|      :.|..|.|....|:.|..|.....:.||.||...:...|:....:..:     .||.
Zfish   190 NS------VLLPSPDELETSEVQDDLETVESVTPDEIHSQDDMEIMDSGSREEMYSNHRENVSET 248

  Fly   411 PDSPQPTAASEIPDLPQTTAINVNPELTQQTALNTIP------HSPQPEASFSTQLVSQTFD 466
            .||.        |:: .....|:.|:       |.:|      |....|..:....|..|.|
Zfish   249 VDSG--------PEI-YNNYNNIMPD-------NDLPEPDDQDHQDGSEVMYLEDFVGSTED 294

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
pie	NP_001260348.1	PHD_SF	9..117	CDD:304600
		PHD_SF	224..>260	CDD:304600
		PARM	318..>491	CDD:293666	35/187 (19%)
si:ch211-37e10.1	XP_017209386.2	UBQ	105..>142	CDD:320785	6/36 (17%)
si:ch211-37e10.1	XP_017209386.2	HECTc	309..659	CDD:331829
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12420
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	2.010