Protein Alignment pie and kmt2ba

DIOPT Version :9

• Sequence 1: NP_001260348.1
• Gene: pie / 44315
• FlyBaseID: FBgn0005683
• Length: 582
• Species: Drosophila melanogaster
• Sequence 2: XP_689347.5
• Gene: kmt2ba / 560856
• ZFINID: ZDB-GENE-060503-376
• Length: 2863
• Species: Danio rerio
• Alignment Length: 559
• Identity: 123/559 - (22%)
• Similarity: 177/559 - (31%)
• Gaps: 169/559 - (30%)

  Fly     6 ELQCLIC------KYSDTDDLVF---GEWMIVRNLQVHYFCLLLSTHLPQRGGDSSGILGFLLRD 61
            |.||.:|      |.:|...|::   .||       .|..|.:.|..:.:..|        .|..
Zfish  1386 ERQCSLCQQHGDAKPNDAGRLLYIGQNEW-------AHVNCCIWSAEVQETNG--------ALLH 1435

  Fly    62 IREEAAAAEKRKCWYCNKIGASLQC--DRCRSLFHLKCGLENRAVFEFCGQYKSYCYKCRPMDDY 124
            :....|.....:|..|.:.||::.|  ..|:|.:|..|...:..||:.  ..|.||||.|.:.:.
Zfish  1436 VHSAVARGRFMRCERCGQTGATVGCCLTSCQSNYHFMCARASNCVFQH--DKKVYCYKHRELINS 1498

  Fly   125 KRQLQSNPPRNATCPICFSSIYKVELHCVVYGDCCRLGFAHKKCMRQYALTSGYYLRCIWCRSER 189
            |.: |.|                              ||  :...|.|....|..||      .:
Zfish  1499 KIE-QGN------------------------------GF--EVVRRVYVDFDGISLR------RK 1524

  Fly   190 FRDSIRLQSVFVPDRDATWEKQRNAYRELHERNL-----KCDQPNCLCPSGRTYNRLSW-VILCC 248
            |...:..:||.|            ....||.:||     .......|.|.|...:|..| .:...
Zfish  1525 FLTGLEPESVNV------------MIGSLHVKNLGVLTELSANSGKLYPVGYQCSRWYWSTVDPR 1577

  Fly   249 SSCAATSAHLKCLVGALRLPKKRERTDFKCSMCLD--VERRIAEGPARTTEETNADGDN------ 305
            ..|..|     |.|..:| |..|.||.   |..:|  ....|...|....:|...|.::
Zfish  1578 RRCRYT-----CKVSEVR-PSTRCRTP---SFMVDQGENHTIVHSPKAQNDEDGTDSESFSPGLP 1633

  Fly   306 --------QVDGS-----FYVQKLGPDAATRSLTQTP-----------VFSEEDESERSSNITVI 346
                    |..||     .|.....|.........:|           ..|:.||:.||:
Zfish  1634 LSTPSKTKQDSGSGGRTPGYPHSRRPAGGMSRPLPSPGNALSTSHHILTISDLDETRRST----- 1693

  Fly   347 FSQPKSNATSERLSLSPPQEEMIVEIP---------------DSPEASPKTSIDENHSPQPIARR 396
                :.::|..|.:..||   :|:..|               .||..||..:.:...|.....||
Zfish  1694 ----RRHSTRSRNASPPP---VILSGPMALRSGGSINPRSLSFSPPVSPLGATENLMSTTSPRRR 1751

  Fly   397 DTSDSPQPIAASEIPDSPQPTAASEIPDLPQTTAINVNPELTQQTALNTIPHSPQPEASFSTQLV 461
            ....|..|.:....|..||....|....||.|  ::.:|.|  |....|.||        .|..|
Zfish  1752 GRPPSLSPSSIISGPSPPQAALRSPSSALPST--VHHSPRL--QQPFTTSPH--------KTDKV 1804

  Fly   462 SQTFDCPQPQEQA---VAKAPNSPSLPKEDPNTLLVLKS 497
            .|.| ..:|:|.|   |.|:.:....|..||:|.:.:.|
Zfish  1805 VQDF-LSEPEEAAGAPVLKSDHDLLSPHFDPDTDVAVAS 1842

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pie	NP_001260348.1	PHD_SF	9..117	CDD:304600	27/118 (23%)
		PHD_SF	224..>260	CDD:304600	7/36 (19%)
		PARM	318..>491	CDD:293666	47/201 (23%)
kmt2ba	XP_689347.5	zf-CXXC	780..823	CDD:251032
		PHD_SF	1016..1062	CDD:304600
		PHD_SF	1064..1112	CDD:304600
		PHD_SF	1149..1206	CDD:304600
		Bromo_ALL-1	1187..1334	CDD:99925
		PHD_SF	1389..1492	CDD:304600	28/119 (24%)
		FYRN	1540..1586	CDD:283589	12/50 (24%)
		FYRC	2561..2646	CDD:295414
		SET	<2677..2863	CDD:225491
		SET	2725..2845	CDD:214614

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910