| Sequence 1: | NP_001260348.1 | Gene: | pie / 44315 | FlyBaseID: | FBgn0005683 | Length: | 582 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | XP_011541131.1 | Gene: | KMT2A / 4297 | HGNCID: | 7132 | Length: | 4005 | Species: | Homo sapiens |
| Alignment Length: | 634 | Identity: | 128/634 - (20%) |
|---|---|---|---|
| Similarity: | 213/634 - (33%) | Gaps: | 184/634 - (29%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 1 MEDNKELQCLIC-KYSDTDDLVFGEWMIV-RNLQVHYFCLLLSTHLPQRGGDSSGILGFLLRDIR 63
Fly 64 EEAAAAEKRKCWYCNKIGASLQC--DRCRSLFHLKCGLENRAVFEFCGQYKSYCYKCRPMDDYKR 126
Fly 127 QLQSNPPRNATCPICFSSIYKVELHCVVYGDCCRLGFAHKKCMRQYALTSGYYLRCIWCRSERFR 191
Fly 192 DSIRLQSVFVPDRDATWEKQRNAYRELHERNLKC-----DQPNC---LCPSGRTYNRLSWVILCC 248
Fly 249 SSCAATSAHLKCLVGALRLPKKRE---RTDFKCSMCLDVERRIAEGPARTTEETNADGDNQVDGS 310
Fly 311 FYVQKLGPDAATRSLT---------------QTPVFSEEDESERSSNITVIFSQPKSNATSERLS 360
Fly 361 LSPPQEEMIVEIPD--------------------SPEASPKTSIDENHSPQPIARRDTSDSPQPI 405
Fly 406 AASEIPDSPQ-------PTAASEIPDLPQTTAINVNPELTQQTALNTIPH-----SPQPEASFST 458
Fly 459 QLVSQTFDCPQPQEQAVAKAPNS--------PSLPKEDP---NT----LLVLKSG-FQCPGE-PF 506
Fly 507 FYLVIYEFEHGTCMGECIGTCVLRFKEDDPRIQDTSQAALERVNITPDD 555 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| pie | NP_001260348.1 | PHD_SF | 9..117 | CDD:304600 | 28/111 (25%) |
| PHD_SF | 224..>260 | CDD:304600 | 10/43 (23%) | ||
| PARM | 318..>491 | CDD:293666 | 42/230 (18%) | ||
| KMT2A | XP_011541131.1 | zf-CXXC | 1180..1227 | CDD:251032 | |
| PHD1_KMT2A | 1466..1512 | CDD:277063 | |||
| PHD2_KMT2A | 1514..1563 | CDD:277065 | |||
| PHD3_KMT2A | 1601..1660 | CDD:277067 | |||
| Bromo_ALL-1 | 1683..1813 | CDD:99925 | |||
| ePHD_KMT2A | 1907..2019 | CDD:277163 | 31/124 (25%) | ||
| FYRN | 2061..2107 | CDD:283589 | 12/54 (22%) | ||
| FYRC | 3705..3788 | CDD:197781 | |||
| SET | <3861..4005 | CDD:225491 | |||
| SET | 3867..3987 | CDD:214614 | |||
| PostSET | 3989..4005 | CDD:214703 | |||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E2759_KOG1084 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 2 | 1.810 | |||||