DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment pie and Phf11b

DIOPT Version :9

Sequence 1:	NP_001260348.1	Gene:	pie / 44315	FlyBaseID:	FBgn0005683	Length:	582	Species:	Drosophila melanogaster
Sequence 2:	XP_006518990.1	Gene:	Phf11b / 236451	MGIID:	3645789	Length:	293	Species:	Mus musculus

Alignment Length:	250	Identity:	57/250 - (22%)
Similarity:	102/250 - (40%)	Gaps:	38/250 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MEDNKELQCLICKYSDTDDLVFGEWMIV-----RNLQVHYFCLLLSTHLPQRGGDS--SGILGFL 58
            :|..::..|.:|....       ||..:     .|:..|..|||.|:.|.:.....  :.|..|.
Mouse    20 IEKMEKRTCALCPEGH-------EWSQIYFSPSGNIVAHENCLLYSSGLVESEAPDLPNTIRNFD 77

  Fly    59 LRDIREEAAAAEKRKCWYCNKIGASLQCD--RCRSLFHLKCGLENRAVF---EFCGQYKSYCYKC 118
            ::.:::|.....:.||.:|...||::.||  .|...:||.|.:|:.|:.   |..|.||.:|.|.
Mouse    78 VKSVKKEIGRGRRLKCSFCKNKGATMGCDLQSCTKNYHLSCAMEDHAILQVDEDHGTYKLFCQKH 142

  Fly   119 RPMDDYKRQLQSNPPRNATCPICF------SSIYKVELHCVVYGDCCRLGFAHKKCMRQYALTSG 177
            .|      :.|....|:||....|      :.:..|.|..::.    ::...|.:.:.:.|..|.
Mouse   143 AP------EAQEPTQRDATVKAPFLKKCQEAGLLNVLLEYILE----KMDLIHGRLLDETASESD 197

  Fly   178 YY-LRCIWCRSERFRDS-IRLQSVFVPDRDATWEKQRNAYRELHERNLKCDQPNC 230
            |. :..:...|..|.|: |:.|.| :..:...||:::...::..|......|..|
Mouse   198 YEGIETLLFESGLFEDTLIQFQEV-IKSKACEWEERQRLMKQQLEALADLQQSLC 251

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
pie	NP_001260348.1	PHD_SF	9..117	CDD:304600	32/119 (27%)
		PHD_SF	224..>260	CDD:304600	1/6 (17%)
		PARM	318..>491	CDD:293666
Phf11b	XP_006518990.1	PHD_SF	28..142	CDD:389947	32/120 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1084
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12420
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	4	3.870