DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment pie and Phf11d

DIOPT Version :9

Sequence 1:	NP_001260348.1	Gene:	pie / 44315	FlyBaseID:	FBgn0005683	Length:	582	Species:	Drosophila melanogaster
Sequence 2:	NP_950180.3	Gene:	Phf11d / 219132	MGIID:	1277133	Length:	320	Species:	Mus musculus

Alignment Length:	289	Identity:	57/289 - (19%)
Similarity:	105/289 - (36%)	Gaps:	72/289 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MEDNKELQCLICKYSDTDDLVFGEWMIV-----RNLQVHYFCLLLSTHLPQ------RGGDSSGI 54
            :|..::..|.:|....       ||..:     .|:..|..|||.|:.|.:      |    :.|
Mouse    20 IEKMEKRTCALCPEGH-------EWSQIYFSPSGNIVAHENCLLYSSGLVECETLDLR----NTI 73

  Fly    55 LGFLLRDIREEAAAAEKRKCWYCNKIGASLQCDR--CRSLFHLKCGLENRAVFEFCGQ---YKSY 114
            ..|.::.:::|.....:.||.:|||.||::.||.  |:..:|..|..:::|:.:..|.   ||.:
Mouse    74 RNFDVKSVKKEIWRGRRLKCSFCNKGGATVGCDLWFCKKSYHYVCAKKDQAILQVDGNHGTYKLF 138

  Fly   115 CYKCRP--------MDD--------YKRQLQSNPPRNATCPICFSSIYKVELHCVVYG------- 156
            |.:..|        .||        ..::|.|.||.......|.::  |..:....:|
Mouse   139 CPEHSPEQEEATESADDPSMKKKRGKNKRLSSGPPAQPKTMKCSNA--KRHMTEEPHGHTDAAVK 201

  Fly   157 -----DCCRLGF--------------AHKKCMRQYALTSGYY-LRCIWCRSERFRDSIRLQSVFV 201
                 .|...|.              .|.:.:.:.|..|.|. :..:......|:|::|.....:
Mouse   202 SPFLKKCQEAGLLTELFEHILENMDSVHGRLVDETASESDYEGIETLLFDCGLFKDTLRKFQEVI 266

  Fly   202 PDRDATWEKQRNAYRELHERNLKCDQPNC 230
            ..:...||:::...::..|......|..|
Mouse   267 KSKACEWEERQRQMKQQLEALADLQQSLC 295

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
pie	NP_001260348.1	PHD_SF	9..117	CDD:304600	32/123 (26%)
		PHD_SF	224..>260	CDD:304600	2/7 (29%)
		PARM	318..>491	CDD:293666
Phf11d	NP_950180.3	PHD_SF	28..142	CDD:304600	32/124 (26%)
Phf11d	NP_950180.3	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	145..196		9/52 (17%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12420
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010