DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Vha16-1 and ATP6V0C

DIOPT Version :9

Sequence 1:	NP_476801.1	Gene:	Vha16-1 / 44307	FlyBaseID:	FBgn0262736	Length:	159	Species:	Drosophila melanogaster
Sequence 2:	NP_001185498.1	Gene:	ATP6V0C / 527	HGNCID:	855	Length:	155	Species:	Homo sapiens

Alignment Length:	154	Identity:	125/154 - (81%)
Similarity:	135/154 - (87%)	Gaps:	2/154 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 SSDNPIYGPFFGVMGAASAIIFSALGAAYGTAKSGTGIAAMSVMRPELIMKSIIPVVMAGIIAIY 70
            |...|.|..||.||||::|::||||||||||||||||||||||||||.|||||||||||||||||
Human     4 SKSGPEYASFFAVMGASAAMVFSALGAAYGTAKSGTGIAAMSVMRPEQIMKSIIPVVMAGIIAIY 68

  Fly    71 GLVVAVLIAGALEEPSKYSLYRGFIHLGAGLAVGFSGLAAGFAIGIVGDAGVRGTAQQPRLFVGM 135
            |||||||||.:|.:  ..|||:.|:.|||||:||.||||||||||||||||||||||||||||||
Human    69 GLVVAVLIANSLND--DISLYKSFLQLGAGLSVGLSGLAAGFAIGIVGDAGVRGTAQQPRLFVGM 131

  Fly   136 ILILIFAEVLGLYGLIVAIYLYTK 159
            ||||||||||||||||||:.|.||
Human   132 ILILIFAEVLGLYGLIVALILSTK 155

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Vha16-1	NP_476801.1	V_ATP_synt_C	15..122	CDD:130170	86/106 (81%)
Vha16-1	NP_476801.1	ATP-synt_Vo_c_ATP6C_rpt2	90..157	CDD:349416	58/66 (88%)
ATP6V0C	NP_001185498.1	V_ATP_synt_C	13..118	CDD:130170	86/106 (81%)
ATP6V0C	NP_001185498.1	ATP-synt_Vo_c_ATP6C_rpt2	86..153	CDD:349416	58/66 (88%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165143869
Domainoid	1	1.000	109	1.000	Domainoid score	I6366
eggNOG	1	0.900	-	-		E1_COG0636
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H68199
Inparanoid	1	1.050	233	1.000	Inparanoid score	I3429
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53914
OrthoDB	1	1.010	-	-		D1534092at2759
OrthoFinder	1	1.000	-	-		FOG0001101
OrthoInspector	1	1.000	-	-		otm40490
orthoMCL	1	0.900	-	-		OOG6_100711
Panther	1	1.100	-	-	LDO	PTHR10263
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X666
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	14	13.810