Protein Alignment ASPA and UFO1

DIOPT Version :10

• Sequence 1: NP_000040.1
• Gene: ASPA / 443
• HGNCID: 756
• Length: 313
• Species: Homo sapiens
• Sequence 2: NP_013622.1
• Gene: UFO1 / 854886
• SGDID: S000004553
• Length: 668
• Species: Saccharomyces cerevisiae
• Alignment Length: 361
• Identity: 64/361 - (17%)
• Similarity: 113/361 - (31%)
• Gaps: 125/361 - (34%)

Human     8 EEHIQKVAIFGGTHGNELTGVFLVKHWLENGAEIQRTGLE------------VKPFITNPRAVKK 60
            :.::..|..|.|.|...:|.:...:.|..:..:...:|.|            ||.:..:.|.:.|
Yeast   180 KSYLTPVMEFTGRHSAGVTAICNSESWDTSREDWSVSGSENGEIIWWCENKLVKMWKVSNRVIWK 244

Human    61 CTRYIDCDLNRIFDLENLGKKMSEDLPYEVRRAQEINHLFGPKDSED--------SYD------I 111
            ...:.|..|  |.|.|.|         |.:.:.||::.:..|||.::        ..|      :
Yeast   245 LAFFKDWTL--IMDDEKL---------YIIHQMQELHSIDIPKDLDEQPMRVRFFKMDFGSMTLV 298

Human   112 IFDLHNT-------------------------------TSNM----------GCTLILEDSRNNF 135
            :.||:|.                               ||..          ||.:.|..::|..
Yeast   299 LADLNNVYTISVNPNGNFGNLRKLEMPEQICAVEIDEKTSQREQNWQFAGDDGCYISLLTTQNTL 363

Human   136 LIQMFHYIKTSLAPLPCYVYLIEHPSLKYATTR-SIAKYPVGIEV-----GPQPQGVLRADILDQ 194
            .|.....:.:|...:.|.:...|...:...|.. .:...|..:::     |...:.||:.:...:
Yeast   364 YIINIRDLSSSGLKVQCKISFDEQVYVSQVTNLIVVVALPNVLQILNAMTGELIKTVLKTEKFPE 428

Human   195 MRKM-----------IKHALDFI-------HHFNEGK--------EFPPCAIEVYKIIEKVDYPR 233
            ..|:           :.:.|.|:       ||..:||        |.....::.|.  |..|..|
Yeast   429 FLKVSQDKIIMGSGNVLNYLKFVSSDSKKHHHSTKGKNTVSNKWNETLNTELQYYD--EDEDLRR 491

Human   234 DENGEIAAIIHPNLQDQDWKPLHPGDPMFLTLDGKT 269
            ....||:.:|          ..:.||   |.|.|.|
Yeast   492 KRQSEISRLI----------DAYGGD---LELSGDT 514

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ASPA	NP_000040.1	Peptidase_M14_like	10..300	CDD:472171	64/359 (18%)
UFO1	NP_013622.1	F-box_ScUFO1-like	6..46	CDD:438916