Protein Alignment ASPA and MET30

DIOPT Version :10

• Sequence 1: NP_000040.1
• Gene: ASPA / 443
• HGNCID: 756
• Length: 313
• Species: Homo sapiens
• Sequence 2: NP_012218.1
• Gene: MET30 / 854765
• SGDID: S000001308
• Length: 640
• Species: Saccharomyces cerevisiae
• Alignment Length: 208
• Identity: 45/208 - (21%)
• Similarity: 64/208 - (30%)
• Gaps: 80/208 - (38%)

Human    90 VRRAQEINHLFGPKDSEDSYDIIFDLHNTTSNMGCTLILEDSRNNFLIQMFHYIKTSLAPLPCYV 154
            :||.::....|..||.:|                    |::|.:|...:|   ..|::.| |...
Yeast     1 MRRERQRMMSFEDKDKDD--------------------LDNSNSNNSSEM---TDTAMMP-PLKR 41

Human   155 YLIEHPSLKYA-----------TTRSIAKYP------VGIEVGPQPQGVLRADILDQMRKMIKHA 202
            .||...|...|           .|||.:..|      .|..|.|.|:               .:.
Yeast    42 LLITGSSDDLAQGSSGKKKMTMATRSPSSSPDLATNDSGTRVQPLPE---------------YNF 91

Human   203 LDFIHHFNEGKEFPPCAIEVYK-----------IIEKVDYPRDENGEIAAII--HPNLQDQDWKP 254
            ..|.:..|...:|.|.....||           .|.|:  |..|..:|..||  :.|..|:..|
Yeast    92 TKFCYRHNPDIQFSPTHTACYKQDLKRTQEINANIAKL--PLQEQSDIHHIISKYSNSNDKIRK- 153

Human   255 LHPGDPMFLTLDG 267
                    |.|||
Yeast   154 --------LILDG 158

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ASPA	NP_000040.1	Peptidase_M14_like	10..300	CDD:472171	45/208 (22%)
MET30	NP_012218.1	F-box_SpPof1-like	183..228	CDD:438918
		WD40	295..590	CDD:238121
		WD40 repeat	305..340	CDD:293791
		WD40 repeat	346..380	CDD:293791
		WD40 repeat	385..418	CDD:293791
		WD40 repeat	425..460	CDD:293791
		WD40 repeat	488..549	CDD:293791