Protein Alignment ASPA and strm-1

DIOPT Version :10

• Sequence 1: NP_000040.1
• Gene: ASPA / 443
• HGNCID: 756
• Length: 313
• Species: Homo sapiens
• Sequence 2: NP_497549.2
• Gene: strm-1 / 175358
• WormBaseID: WBGene00019198
• Length: 334
• Species: Caenorhabditis elegans
• Alignment Length: 272
• Identity: 55/272 - (20%)
• Similarity: 94/272 - (34%)
• Gaps: 98/272 - (36%)

Human     4 CHIAE-----EHIQKVAI---FGGT------HGNELTGVFLVKHWLENGAEIQRTGLEVKPFITN 54
            |||||     |::..:.|   .||.      .|.:||||.:..:..|.|.|          ...|
 Worm    85 CHIAEKLELSENVHCLDIGCGIGGVMLDIADFGAKLTGVTIAPNEAEIGNE----------KFAN 139

Human    55 PRAVKKCTRYIDCDLNRI------FD----------LENLGKKMSE----------DLPYEVRRA 93
            .....:| :.:..|..::      ||          :.||.|.|.|          .:.|::.:.
 Worm   140 MGISDRC-KIVAADCQKMPFEDSTFDVAYAIYSLKYIPNLDKVMKEIQRVLKPGGKFIVYDLIKT 203

Human    94 QEINHLFGPKDSEDSYDIIFDLH--------NTTSNMGCTL-----------ILEDSRNNFLIQM 139
            .:.:     ||:::.|..:..|.        :|.|.:....           .||::..|   :.
 Worm   204 NDYD-----KDNKEHYKTLHHLEYACGMPSLHTQSEVEAAAEKWEMPVVERENLEETYGN---RA 260

Human   140 FHYIKTSLAPLPCYVYLIEHPSLKYATTRS--IAKYPVGIE--------------VGPQPQGVLR 188
            |||   ..:..|.:::|:..|.:.:....:  :...|.|.:              ||....|:|.
 Worm   261 FHY---CFSASPMFMWLVSSPVIDHTIRMAEILRILPAGFKQFNRTFLCGTVNSIVGGGRMGILS 322

Human   189 -ADILDQMRKMI 199
             ||||...:|.|
 Worm   323 GADILLFEKKKI 334

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ASPA	NP_000040.1	Peptidase_M14_like	10..300	CDD:472171	49/261 (19%)
strm-1	NP_497549.2	UbiE	86..207	CDD:441828	27/131 (21%)