Protein Alignment ome and DAP2

DIOPT Version :10

• Sequence 1: NP_001097606.1
• Gene: ome / 44297
• FlyBaseID: FBgn0259175
• Length: 1040
• Species: Drosophila melanogaster
• Sequence 2: NP_011893.1
• Gene: DAP2 / 856423
• SGDID: S000001070
• Length: 818
• Species: Saccharomyces cerevisiae
• Alignment Length: 829
• Identity: 232/829 - (27%)
• Similarity: 383/829 - (46%)
• Gaps: 120/829 - (14%)

  Fly   258 HTKEKKRRVRIILTVVTTVIAVALLATALVFILR-----TDEKDADDSDSNSNN----AIDLEDV 313
            |..:|..||.|||         .||....|.:|:     ::..|..:.:||..|    .:....|
Yeast    22 HLLDKLIRVGIIL---------VLLIWGTVLLLKSIPHHSNTPDYQEPNSNYTNDGKLKVSFSVV 77

  Fly   314 LSGQLYAKRFNGSWSNGNSL--------------------IYKENTSIMEFDAKTGERSILLEDA 358
            .:.....|.....|.:.|.:                    :|.::.:.:..:.||     .:.:.
Yeast    78 RNNTFQPKYHELQWISDNKIESNDLGLYVTFMNDSYVVKSVYDDSYNSVLLEGKT-----FIHNG 137

  Fly   359 QHYVL--YEKSADGEFLLLAKNYKKNFRYSFLAEYDLYNLNTKEFIQLTIQNEQHYLSMVQWSPV 421
            |:..:  ...|.|.:.||:..|..:|:|:|....|.:|:.::..|.:  |.||   :::..|||.
Yeast   138 QNLTVESITASPDLKRLLIRTNSVQNWRHSTFGSYFVYDKSSSSFEE--IGNE---VALAIWSPN 197

  Fly   422 GNALVINYDRNLYYKESALAQEI--ALTSDEQAGILNGIPDWVYEEEVFSSNVATWFNPSGTQLA 484
            .|.:....|.|:|. .||::::.  |:|:|..:.:.||.||||||||||..:.|.|::|:|..||
Yeast   198 SNDIAYVQDNNIYI-YSAISKKTIRAVTNDGSSFLFNGKPDWVYEEEVFEDDKAAWWSPTGDYLA 261

  Fly   485 FIKFDDSSTHLINFPYY-GDAGDLRYQYPLHQVIAYPKAGSSNPRVELVMVDLKRAVAGGDFVTV 548
            |:|.|:|.......||| .|..|:   ||..:.|.|||:|:.||..||.:..:|      |..:.
Yeast   262 FLKIDESEVGEFIIPYYVQDEKDI---YPEMRSIKYPKSGTPNPHAELWVYSMK------DGTSF 317

  Fly   549 MPVPSALNTETDYIVTVVSWVDDDNVLSIWMNRIQNAAYVVTFDGLNR--KVIYSAESKTGWVDL 611
            .|..|....:...::|.|:||.:.|||....:|..:...|...|.:.:  .|:.:..|..||.::
Yeast   318 HPRISGNKKDGSLLITEVTWVGNGNVLVKTTDRSSDILTVFLIDTIAKTSNVVRNESSNGGWWEI 382

  Fly   612 -YTAPF--------RNRNGSRLAFVLPHNNYKHVQLLSSTVASSEPQALEPLTEGKY-VVDSILH 666
             :...|        |..||  ...:||...|.|:....::.:|.    .:.|||||: ||:..|.
Yeast   383 THNTLFIPANETFDRPHNG--YVDILPIGGYNHLAYFENSNSSH----YKTLTEGKWEVVNGPLA 441

  Fly   667 WDGKNDIIFYTANTEDHPEQLHLYAIRALAKQSPKCLTCNLIKSGDVQQT-YFSATFNDNNHI-V 729
            :|...:.:::.:..:...|: |:|.|..   :||.    .:|:..|..:. .:..:|:..... :
Yeast   442 FDSMENRLYFISTRKSSTER-HVYYIDL---RSPN----EIIEVTDTSEDGVYDVSFSSGRRFGL 498

  Fly   730 ITSLGPGIPTTHIYEW------KYENSQVVISKVLDWETNESLRAKLKGVALP--SHKILTVDID 786
            :|..||.:|...|.::      |.:...|:...:...|.||.|...|:..|:|  |.:.|.:..|
Yeast   499 LTYKGPKVPYQKIVDFHSRKAEKCDKGNVLGKSLYHLEKNEVLTKILEDYAVPRKSFRELNLGKD 563

  Fly   787 GGFQAKVLLQ----LPPNLDTSGATKYPMLVDVYGGPDSYSVTNKWMVDWGTYLSSNQSVIYAKI 847
             .|...:|:.    ||.:.|.:.:..||:....||||:|..|...:.|.:...::|..:.|...:
Yeast   564 -EFGKDILVNSYEILPNDFDETLSDHYPVFFFAYGGPNSQQVVKTFSVGFNEVVASQLNAIVVVV 627

  Fly   848 DGRGSGLRGESLLHAIYLKLGTVEISDQINVTQKLSTLFNYIDPDHVGIWGWSYGGYAAAMALAN 912
            ||||:|.:|:.....:..:||..|..|||:......:| .::||..:.::|||||||.....|..
Yeast   628 DGRGTGFKGQDFRSLVRDRLGDYEARDQISAASLYGSL-TFVDPQKISLFGWSYGGYLTLKTLEK 691

  Fly   913 DEAKVFKCAASIAPVTDWAYYDSIYTERYMGLPNTNELGYANSRLSTMAVKLRGKKYLLVHGTLD 977
            |..:.||...|:||||||.:|||:||||||..|..|..||..|.:..:....:..::||:|||.|
Yeast   692 DGGRHFKYGMSVAPVTDWRFYDSVYTERYMHTPQENFDGYVESSVHNVTALAQANRFLLMHGTGD 756

  Fly   978 DNVHYQQAM----ILAKN-LERQDILFKQISYADEDHGLSNVRPHLYHS 1021
            ||||:|.::    :|..| :|..|:..    :.|.||.:.      ||:
Yeast   757 DNVHFQNSLKFLDLLDLNGVENYDVHV----FPDSDHSIR------YHN 795

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ome	NP_001097606.1	DPPIV_N	367..739	CDD:395744	112/388 (29%)
		Peptidase_S9	828..1033	CDD:459761	70/199 (35%)
DAP2	NP_011893.1	DPPIV_N	148..508	CDD:395744	112/388 (29%)
		Peptidase_S9	608..815	CDD:459761	70/199 (35%)