Protein Alignment ome and DPP10

DIOPT Version :10

• Sequence 1: NP_001097606.1
• Gene: ome / 44297
• FlyBaseID: FBgn0259175
• Length: 1040
• Species: Drosophila melanogaster
• Sequence 2: NP_001308834.2
• Gene: DPP10 / 57628
• HGNCID: 20823
• Length: 813
• Species: Homo sapiens
• Alignment Length: 798
• Identity: 245/798 - (30%)
• Similarity: 399/798 - (50%)
• Gaps: 77/798 - (9%)

  Fly   263 KRRVRIILTVVTTVIAVALLATALVFILRTDEKDADDSDSNSNNAIDLEDVLSGQLYAKRF---- 323
            :|..:.|...:..::.|..|.|..|.:|..||     ..::|...:.|||     |:.|.|
Human    46 QRNWKGIAIALLVILVVCSLITMSVILLTPDE-----LTNSSETRLSLED-----LFRKDFVLHD 100

  Fly   324 -NGSWSNGNSLIYK-ENTSIMEFDAKTGERSILLED--------AQHYVLYEKSADGEFLLLAKN 378
             ...|.|...::|| ||..:::.:.:|...::|||:        ::|.|    |.|.:::|||.:
Human   101 PEARWINDTDVVYKSENGHVIKLNIETNATTLLLENTTFVTFKASRHSV----SPDLKYVLLAYD 161

  Fly   379 YKKNFRYSFLAEYDLYNLNTKEFIQLT-IQNEQHYLSMVQWSPVGNALVINYDRNLYYKESALAQ 442
            .|:.|.||:.|.|.:||::|:|..:|. .:.|...|....|...|..|:..::.|:||:....:.
Human   162 VKQIFHYSYTASYVIYNIHTREVWELNPPEVEDSVLQYAAWGVQGQQLIYIFENNIYYQPDIKSS 226

  Fly   443 EIALTSD-EQAGILNGIPDWVYEEEVFSSNVATWFNPSGTQLAFIKFDDSSTHLINFPYYGDAGD 506
            .:.|||. ::..|.|||.||:||||:..|::|.|::|.|.:|||:..:||....:..|.:..|
Human   227 SLRLTSSGKEEIIFNGIADWLYEEELLHSHIAHWWSPDGERLAFLMINDSLVPTMVIPRFTGA-- 289

  Fly   507 LRYQYPLHQVIAYPKAGSSNPRVELVMVDLKRAVAGGDFVTVMPVPSALNTETDYIVTVVSWVDD 571
               .||..:...|||||..||.::|.:|:|.     |...|:..:|.......:|.:|:|.||.:
Human   290 ---LYPKGKQYPYPKAGQVNPTIKLYVVNLY-----GPTHTLELMPPDSFKSREYYITMVKWVSN 346

  Fly   572 DNVLSIWMNRIQNAAYV----VTFDGLNRKVIYSAESKTGWVDLYTAPFRNRNGSRLAFVLP--- 629
            ...:..|:||.||.:.:    .|....::|  |...|.|........|..:|:||:....:|
Human   347 TKTVVRWLNRAQNISILTVCETTTGACSKK--YEMTSDTWLSQQNEEPVFSRDGSKFFMTVPVKQ 409

  Fly   630 --HNNYKHVQ--LLSSTVASSEPQALEPLTEGKYVVDSILHWDGKNDIIFYTANTEDHPEQLHLY 690
              ...:.||.  |:.|   .||...:..||.|.:.|..||.:|.....|:: .:||..|....||
Human   410 GGRGEFHHVAMFLIQS---KSEQITVRHLTSGNWEVIKILAYDETTQKIYF-LSTESSPRGRQLY 470

  Fly   691 AIRALAKQSPKCLTCNLIKSGDVQQTYFSATFND-NNHIVITSLGPGIPTTHIYEWKYENSQVVI 754
            :.......:.:|::||.:|.   |.|||.|:|:. |.|.::...||.:|...::  ..:|.
Human   471 SASTEGLLNRQCISCNFMKE---QCTYFDASFSPMNQHFLLFCEGPRVPVVSLH--STDNP---- 526

  Fly   755 SKVLDWETNESLRAKL--KGVALPSHKILTVDIDGGFQAKVLLQLPPNLDTSGATKYPMLVDVYG 817
            :|....|:|..|:..:  |.:..|..|||.:|   .::..:.|.||.  |.....:|.:|:.:..
Human   527 AKYFILESNSMLKEAILKKKIGKPEIKILHID---DYELPLQLSLPK--DFMDRNQYALLLIMDE 586

  Fly   818 GPDSYSVTNKWMVDWGTYLSSNQSVIYAKIDGRGSGLRGESLLHAIYLKLGTVEISDQINVTQKL 882
            .|....||:|:.:||.:.|....:||.|:.||||||.:|..:|..|:.:||:||:.|||...:.|
Human   587 EPGGQLVTDKFHIDWDSVLIDMDNVIVARFDGRGSGFQGLKILQEIHRRLGSVEVKDQITAVKFL 651

  Fly   883 STLFNYIDPDHVGIWGWSYGGYAAAMALANDEAKVFKCAASIAPVTDWAYYDSIYTERYMGLPNT 947
            ..| .|||...:.|:|..||||.|:|.|.:|| |:|||.:.:||:||...|.|.::|||:|:|:.
Human   652 LKL-PYIDSKRLSIFGKGYGGYIASMILKSDE-KLFKCGSVVAPITDLKLYASAFSERYLGMPSK 714

  Fly   948 NELGYANSRLSTMAVKLRGKKYLLVHGTLDDNVHYQQAMILAKNLERQDILFKQISYADEDHGLS 1012
            .|..|..:.:......|:.:..|::|||.|..||:|.:..|.|:|.:..:.:....|.||.|.:|
Human   715 EESTYQAASVLHNVHGLKEENILIIHGTADTKVHFQHSAELIKHLIKAGVNYTMQVYPDEGHNVS 779

  Fly  1013 -NVRPHLYHSLDRFFGEC 1029
             ..:.|||.::.:||.:|
Human   780 EKSKYHLYSTILKFFSDC 797

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ome	NP_001097606.1	DPPIV_N	367..739	CDD:395744	117/385 (30%)
		Peptidase_S9	828..1033	CDD:459761	78/203 (38%)
DPP10	NP_001308834.2	DPPIV_N	150..516	CDD:395744	117/384 (30%)
		Peptidase_S9	597..799	CDD:459761	78/203 (38%)