Protein Alignment ome and dpf-2

DIOPT Version :10

• Sequence 1: NP_001097606.1
• Gene: ome / 44297
• FlyBaseID: FBgn0259175
• Length: 1040
• Species: Drosophila melanogaster
• Sequence 2: NP_510461.1
• Gene: dpf-2 / 181579
• WormBaseID: WBGene00001055
• Length: 829
• Species: Caenorhabditis elegans
• Alignment Length: 862
• Identity: 228/862 - (26%)
• Similarity: 372/862 - (43%)
• Gaps: 162/862 - (18%)

  Fly   268 IILTVVTTVIAVALLATALVFILRTDEKDADDSDSNSNNAID-------------------LEDV 313
            :.:.::..:...:::.|.:...:..:..:..:..|.:.::::                   .|.:
 Worm    30 VFILIICVIFVFSVIFTFMQNPINLNSDNGFNQTSGNTSSLEATTLKPKFSSLMTTTRRFTFEQL 94

  Fly   314 LSG-QLYAKRFNGSWSNGNSLIYKENTSIMEFDAKTGERSILLEDAQHYVLYEKSADGEFLLLAK 377
            .|| |.....::..|....|.:...:    :|..:...:.|.|..:.....:.   :||::   |
 Worm    95 FSGKQFLVDYYDYIWLPDGSFVQMND----DFTIRKQMKKIPLGSSVAEPFFN---NGEYV---K 149

  Fly   378 NYKKNFRYSF-----------LAEYDLYN---LNTKEFIQLTIQNEQHYL-----SMVQ---WSP 420
            ....|.:|::           .||| ||:   :|.|     |:..||.::     |::|   |:|
 Worm   150 ALSSNMKYAYGSKKVNELWRHSAEY-LYHIVKINNK-----TVSTEQWHVGPEENSLIQAFYWNP 208

  Fly   421 --VGNALVINYDRNLYYKESALAQEIALTSDEQAGILN--GIPDWVYEEEVFSSNVATWFNPSGT 481
              ..|..|..::.||||::.....:.|:.........|  |:.:|:||||:..::.|.|::|||.
 Worm   209 NASSNDFVYVHNYNLYYQKDPEKPDGAIQLTVGGSTFNRFGLANWLYEEEILEASSAVWWSPSGR 273

  Fly   482 QLAFIKFDDSSTHLINFPYYGDAGDLRYQYPLHQVIAYPKAG-SSNPRVELVMVDLKRAVAGGDF 545
            .:::::|||...:.|..|.|.|..    .|..:..:.||||| .:|..|...:.|.:    ....
 Worm   274 YVSYLRFDDREVNRIFLPKYTDDD----SYVEYFELPYPKAGVQNNTLVTQYIWDSE----NHKI 330

  Fly   546 VTVMPVPSALNTET-DYIVTVVSWV---------DDDNVLSIWMNRIQNAAYVVTFDGLNRKVIY 600
            |...| |:.|:... ||.|....|:         .::.::::|.||.||..|   |...|.:...
 Worm   331 VETAP-PNELSAANGDYYVLTNKWITMPRNGSDLGEERLVTVWANRDQNHVY---FSLCNEQDCV 391

  Fly   601 SAESKTGWVD---LYTAP------FRNRNGSRLAFVLPH-----NNYKHVQLLSSTVASSEPQAL 651
            .|.|....:|   |:.:|      |....|  ...||||     |.|.||..:.          |
 Worm   392 MALSFQFSIDNRQLWVSPKDVRGVFPTETG--FLTVLPHKHDDGNIYNHVAHVE----------L 444

  Fly   652 EPLTEGKYVVDSILHWDGKN-DIIF---YTANTE--------DHPEQLHLYAIR---------AL 695
            :....||     |..|.|:| |:|.   |::..:        |...:...|.:|         .|
 Worm   445 DGTGTGK-----ITKWIGENFDVILVLGYSSKIDALTFSAYGDGVGEFSTYIVREAMYSNKKTTL 504

  Fly   696 AKQSPKCLTCNLIKSGDVQQTYFSATFNDNNHIVITSLGPGIPTTHIYEWKYENSQVVISKVLDW 760
            .|.:.:...|..:.|.....|        ...||:....|           ::|:::.:..|:|.
 Worm   505 QKVTDQFEDCKTLGSQSADPT--------GQRIVVQCEKP-----------FDNTRLYLVDVVDT 550

  Fly   761 ETNESLRAKLKGVA---LPSHKILTVDIDGGFQAKVLLQLPPNLDTSGATKYPMLVDVYGGPDSY 822
            .....|....|.|.   :|:.|...:.:..|.....::..|.|| ..|| |.|:|:|:||||||.
 Worm   551 TKKIMLEGGTKAVIPFDVPNMKFGKLKLPSGIDGHYMMLTPANL-LDGA-KIPLLLDIYGGPDSK 613

  Fly   823 SVTNKWMVDWGTYLSSNQSVIYAKIDGRGSGLRGESLLHAIYLKLGTVEISDQINVTQKLSTLFN 887
            .|..|........:.|...:.||:||.||:|.||..:..|:|.|||..|:.|.:::.:.....|.
 Worm   614 QVFQKTPTAHAIQIVSQYDIAYARIDVRGTGGRGWDVKEAVYRKLGDAEVVDTLDMIRAFINTFG 678

  Fly   888 YIDPDHVGIWGWSYGGYAAAMALANDEAKVFKCAASIAPVTDWAYYDSIYTERYMGLPNTNELGY 952
            :||.|.:.:.||||||:..:.....|:.::.|||.|||||||:.||||.|||||:|.|..|..||
 Worm   679 FIDEDRIAVMGWSYGGFLTSKIAIKDQGELVKCAISIAPVTDFKYYDSAYTERYLGQPAENLQGY 743

  Fly   953 ANSRLSTMAVKLRGKKYLLVHGTLDDNVHYQQAMILAKNLERQDILFKQISYADEDHGLSNVRPH 1017
            .|:.:...|..:...||||.||..|||||||.:...::.|::..|.|.|:.||:|.|.||:...|
 Worm   744 INTNVIPHARNVTNVKYLLAHGERDDNVHYQNSARWSEALQQNGIHFTQLVYANEAHSLSHKLFH 808

  Fly  1018 LYHSLDRF-FGECFASS 1033
            ||..:.|| ..:||.|:
 Worm   809 LYGEVQRFLMNDCFKSN 825

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ome	NP_001097606.1	DPPIV_N	367..739	CDD:395744	106/443 (24%)
		Peptidase_S9	828..1033	CDD:459761	84/205 (41%)
dpf-2	NP_510461.1	DPPIV_N	152..536	CDD:395744	102/426 (24%)
		Peptidase_S9	625..801	CDD:459761	74/175 (42%)