Protein Alignment Idh and LYS12

DIOPT Version :10

• Sequence 1: NP_001137910.2
• Gene: Idh / 44291
• FlyBaseID: FBgn0001248
• Length: 479
• Species: Drosophila melanogaster
• Sequence 2: NP_012172.1
• Gene: LYS12 / 854714
• SGDID: S000001356
• Length: 371
• Species: Saccharomyces cerevisiae
• Alignment Length: 379
• Identity: 92/379 - (24%)
• Similarity: 152/379 - (40%)
• Gaps: 72/379 - (18%)

  Fly    75 DVLGDEMT---RIIWDSIKSQLILPFLDIELHTYDLGIENRDKTEDQVTIDCAEAIKKYNVGIKC 136
            |.:|.|:.   :.:.:::.|:..|.|..|:|:.   |.:...:|...:..:..:.:|:...|...
Yeast    32 DGIGKEVIPAGKQVLENLNSKHGLSFNFIDLYA---GFQTFQETGKALPDETVKVLKEQCQGALF 93

  Fly   137 ATITPDEKRVEEFNLKKMWKSPNGTIRNILGGTVFREAIICKNV--PRLVTGWQ-KPI--VIGRH 196
            ..:.....:||.::      ||...:|        ||..:..||  .:.|.|.: |||  ||.|.
Yeast    94 GAVQSPTTKVEGYS------SPIVALR--------REMGLFANVRPVKSVEGEKGKPIDMVIVRE 144

  Fly   197 AHADQYKAVDYVVPGPGKLTLTWKGTDGQVIDEV--INDFKGPGIALGMFNTDDSIVDFAHASFK 259
            ...|.|..::        .|...|.|..:|.|..  |::.....||.              .:..
Yeast   145 NTEDLYIKIE--------KTYIDKATGTRVADATKRISEIATRRIAT--------------IALD 187

  Fly   260 YALDR-----KLPLYMSTKNTILKKYDGRFKDIFEDLYNKQYKKEYEAAGIWYEHRLIDDMVAYA 319
            .||.|     :..|.::.|:.:|.:.||.|::|.:::|... |.:|  ..|.|..:::|.||...
Yeast   188 IALKRLQTRGQATLTVTHKSNVLSQSDGLFREICKEVYESN-KDKY--GQIKYNEQIVDSMVYRL 249

  Fly   320 MKSEGGF-VWACKNYDGDVQSDSVAQGYGSLGLMTSVLLCPDGKTVEAEAAHGTVTRHFRFYQQG 383
            .:....| |....|..||:.||..|...||||::.|..:.|:  .|..|..||:...     ..|
Yeast   250 FREPQCFDVIVAPNLYGDILSDGAAALVGSLGVVPSANVGPE--IVIGEPCHGSAPD-----IAG 307

  Fly   384 KETSTNPIASIFAWTRGLLHRAKLDNNEPLKQFADTLEQVCIDTIESGAMTKDL 437
            |..: ||||:|.:..   |....|.:||..:   |..:.|..:..|....|.||
Yeast   308 KGIA-NPIATIRSTA---LMLEFLGHNEAAQ---DIYKAVDANLREGSIKTPDL 354

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Idh	NP_001137910.2	PTZ00435	63..474	CDD:240417	92/379 (24%)
LYS12	NP_012172.1	LeuB	23..371	CDD:440241	92/379 (24%)