DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Idh and AT5G14590

DIOPT Version :9

Sequence 1:	NP_001137910.2	Gene:	Idh / 44291	FlyBaseID:	FBgn0001248	Length:	479	Species:	Drosophila melanogaster
Sequence 2:	NP_196963.2	Gene:	AT5G14590 / 831311	AraportID:	AT5G14590	Length:	485	Species:	Arabidopsis thaliana

Alignment Length:	474	Identity:	274/474 - (57%)
Similarity:	343/474 - (72%)	Gaps:	12/474 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MFALRRTAAMMTSVHRQPHLSQAVFRANF---AISAADPKTHKIS--MDNERMSAVSEHSSVVCS 60
            :|..|.:...|.|......||.:...:.|   .|.::....::::  :...|.|||...:|...|
plant     9 VFTYRASLTAMLSSSTSAGLSSSFVSSRFLSSGIFSSGASRNRVTFPVQFHRASAVRCFASSGGS 73

  Fly    61 PEQMAQKIKAGPVVDVLGDEMTRIIWDSIKSQLILPFLDIELHTYDLGIENRDKTEDQVTIDCAE 125
            .....|    .|:|::.||||||:||..||.:||||:||:::..:||||.|||.|:|:||::.||
plant    74 DRIQVQ----NPIVEMDGDEMTRVIWSMIKEKLILPYLDLDIKYFDLGILNRDATDDKVTVESAE 134

  Fly   126 AIKKYNVGIKCATITPDEKRVEEFNLKKMWKSPNGTIRNILGGTVFREAIICKNVPRLVTGWQKP 190
            |..||||.||||||||||.||:||.||.||:||||||||||.||||||.|:|.|:||||.||:||
plant   135 AALKYNVAIKCATITPDEGRVKEFGLKSMWRSPNGTIRNILDGTVFREPIMCSNIPRLVPGWEKP 199

  Fly   191 IVIGRHAHADQYKAVDYVVPGPGKLTLTWKGTDGQVIDEV-INDFKGPGIALGMFNTDDSIVDFA 254
            |.|||||..|||:|.|.|:.|||||.:.:...||....|: :.||||||:||.|:|.|:||..||
plant   200 ICIGRHAFGDQYRATDTVIKGPGKLKMVFVPEDGNAPVELDVYDFKGPGVALAMYNVDESIRAFA 264

  Fly   255 HASFKYALDRKLPLYMSTKNTILKKYDGRFKDIFEDLYNKQYKKEYEAAGIWYEHRLIDDMVAYA 319
            .:|...||.:|.|||:||||||||||||||||||:::|...:|:::|...|||||||||||||||
plant   265 ESSMAMALTKKWPLYLSTKNTILKKYDGRFKDIFQEVYEANWKQKFEEHSIWYEHRLIDDMVAYA 329

  Fly   320 MKSEGGFVWACKNYDGDVQSDSVAQGYGSLGLMTSVLLCPDGKTVEAEAAHGTVTRHFRFYQQGK 384
            :|||||:||||||||||||||.:|||:|||||||||||..||||:|:||||||||||||.:|:|:
plant   330 VKSEGGYVWACKNYDGDVQSDLLAQGFGSLGLMTSVLLSADGKTLESEAAHGTVTRHFRLHQKGQ 394

  Fly   385 ETSTNPIASIFAWTRGLLHRAKLDNNEPLKQFADTLEQVCIDTIESGAMTKDLAICIKGNINAVT 449
            |||||.|||||||||||.||||||.||.|..|...||..|::|:|:|.||||||:.|.|  ..|:
plant   395 ETSTNSIASIFAWTRGLEHRAKLDKNEKLMDFVKKLESSCVNTVETGKMTKDLALLIHG--PKVS 457

  Fly   450 RRDYQETFEFINTLAKNLE 468
            |..:..|.|||:.:|..|:
plant   458 RDLFLNTEEFIDAVASKLK 476

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Idh	NP_001137910.2	PTZ00435	63..474	CDD:240417	260/407 (64%)
AT5G14590	NP_196963.2	PLN03065	1..485	CDD:178617	274/474 (58%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	533	1.000	Domainoid score	I60
eggNOG	1	0.900	-	-		E1_COG0538
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	553	1.000	Inparanoid score	I253
OMA	1	1.010	-	-		QHG62611
OrthoDB	1	1.010	-	-		D769322at2759
OrthoFinder	1	1.000	-	-		FOG0001185
OrthoInspector	1	1.000	-	-		otm2951
orthoMCL	1	0.900	-	-		OOG6_100639
Panther	1	1.100	-	-	O	PTHR11822
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X809
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	13	12.840