Protein Alignment Idh and idh2

DIOPT Version :9

• Sequence 1: NP_001137910.2
• Gene: Idh / 44291
• FlyBaseID: FBgn0001248
• Length: 479
• Species: Drosophila melanogaster
• Sequence 2: NP_001004799.1
• Gene: idh2 / 448026
• XenbaseID: XB-GENE-976315
• Length: 455
• Species: Xenopus tropicalis
• Alignment Length: 440
• Identity: 272/440 - (61%)
• Similarity: 334/440 - (75%)
• Gaps: 15/440 - (3%)

  Fly    49 SAVSEHSSVVC---SPEQMAQ-------KIK-AGPVVDVLGDEMTRIIWDSIKSQLILPFLDIEL 102
            :|:.::..|:.   |.:|:.|       :|| |.|||::.|||||||||:.||.:|||..:|:||
 Frog    17 AALGKNPGVLAPALSQQQLQQQRNYADKRIKVANPVVEMDGDEMTRIIWEFIKEKLILSNVDVEL 81

  Fly   103 HTYDLGIENRDKTEDQVTIDCAEAIKKYNVGIKCATITPDEKRVEEFNLKKMWKSPNGTIRNILG 167
            ..:|||:..||:|.||||||.|.|..||||.:|||||||||.|||||.|||||||||||||||||
 Frog    82 KYFDLGLPYRDQTNDQVTIDSALATLKYNVAVKCATITPDEARVEEFKLKKMWKSPNGTIRNILG 146

  Fly   168 GTVFREAIICKNVPRLVTGWQKPIVIGRHAHADQYKAVDYVVPGPGKLTLTWKGTDGQVID--EV 230
            |||||:.|||||:||||.||.:.|.||||||.|||||.|:||...|...|.:...:|....  ||
 Frog   147 GTVFRDPIICKNIPRLVPGWTQAITIGRHAHGDQYKATDFVVDQAGTFKLVFAPANGTATKEWEV 211

  Fly   231 INDFKGPGIALGMFNTDDSIVDFAHASFKYALDRKLPLYMSTKNTILKKYDGRFKDIFEDLYNKQ 295
            .| |...|:.:||:|||:||..|||:.|:|::.:|.|||:||||||||.|||||||||:|::.|.
 Frog   212 FN-FPAGGVGMGMYNTDESISGFAHSCFQYSIQKKWPLYLSTKNTILKAYDGRFKDIFQDIFEKH 275

  Fly   296 YKKEYEAAGIWYEHRLIDDMVAYAMKSEGGFVWACKNYDGDVQSDSVAQGYGSLGLMTSVLLCPD 360
            ||.|::...|||||||||||||..:||.|||||||||||||||||.:|||:||||||||||:|||
 Frog   276 YKPEFDKLKIWYEHRLIDDMVAQVLKSTGGFVWACKNYDGDVQSDILAQGFGSLGLMTSVLVCPD 340

  Fly   361 GKTVEAEAAHGTVTRHFRFYQQGKETSTNPIASIFAWTRGLLHRAKLDNNEPLKQFADTLEQVCI 425
            |||:||||||||||||:|.:|:|:.||||||||||||||||.||.|||.|:.|..|:.|||:||:
 Frog   341 GKTIEAEAAHGTVTRHYREHQKGRPTSTNPIASIFAWTRGLEHRGKLDGNQDLINFSLTLEKVCV 405

  Fly   426 DTIESGAMTKDLAICIKGNINAVTRRD-YQETFEFINTLAKNLEGALAKN 474
            :|:|||.||||||.||.|.::.|...: |..|.:|::.:..||:.||.||
 Frog   406 ETVESGIMTKDLAGCIHGGMSNVRLNEHYVNTTDFLDAIKNNLDKALGKN 455

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Idh	NP_001137910.2	PTZ00435	63..474	CDD:240417	267/421 (63%)
idh2	NP_001004799.1	PTZ00435	41..455	CDD:240417	265/414 (64%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D248894at33208
OrthoFinder	1	1.000	-	-		FOG0001185
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5145
SonicParanoid	1	1.000	-	-		X809
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.040