Protein Alignment Idh and idh-2

DIOPT Version :9

• Sequence 1: NP_001137910.2
• Gene: Idh / 44291
• FlyBaseID: FBgn0001248
• Length: 479
• Species: Drosophila melanogaster
• Sequence 2: NP_001370015.1
• Gene: idh-2 / 181311
• WormBaseID: WBGene00007942
• Length: 435
• Species: Caenorhabditis elegans
• Alignment Length: 410
• Identity: 267/410 - (65%)
• Similarity: 319/410 - (77%)
• Gaps: 2/410 - (0%)

  Fly    56 SVVCSPEQMAQKIKA-GPVVDVLGDEMTRIIWDSIKSQLILPFLDIELHTYDLGIENRDKTEDQV 119
            :|..:..|..||||. .||||:.|||||||||..||::||||:||:::..||||:|.||:|.|||
 Worm    15 NVATAATQERQKIKVDNPVVDLDGDEMTRIIWKEIKNKLILPYLDLDIKYYDLGLEYRDETNDQV 79

  Fly   120 TIDCAEAIKKYNVGIKCATITPDEKRVEEFNLKKMWKSPNGTIRNILGGTVFREAIICKNVPRLV 184
            |||.|.||.:::||||||||||||.|::||||||||.|||||||||||||||||.|:|||:||||
 Worm    80 TIDAAHAILEHSVGIKCATITPDEARIKEFNLKKMWLSPNGTIRNILGGTVFREPILCKNIPRLV 144

  Fly   185 TGWQKPIVIGRHAHADQYKAVDYVVPGPGKLTLTWKGTDGQVIDEVINDF-KGPGIALGMFNTDD 248
            .||.:||.|||||..||||..|.|:|....|.|.....||......:.|| |..|:.|.|:|||:
 Worm   145 PGWTQPITIGRHAFGDQYKCTDLVIPSGSTLQLLVNKPDGSKDVHNVYDFKKSGGVGLAMYNTDE 209

  Fly   249 SIVDFAHASFKYALDRKLPLYMSTKNTILKKYDGRFKDIFEDLYNKQYKKEYEAAGIWYEHRLID 313
            ||..|||:.|:|||.::.|||:||||||||||||||||||:|:|.|:|:.:::...|||||||||
 Worm   210 SIKGFAHSCFQYALMKQWPLYLSTKNTILKKYDGRFKDIFQDIYEKKYEADFKNNKIWYEHRLID 274

  Fly   314 DMVAYAMKSEGGFVWACKNYDGDVQSDSVAQGYGSLGLMTSVLLCPDGKTVEAEAAHGTVTRHFR 378
            |.||.|:||.|||||||||||||||||.|||||||||||:|||:||||||:||||||||||||:|
 Worm   275 DQVAQALKSSGGFVWACKNYDGDVQSDIVAQGYGSLGLMSSVLMCPDGKTIEAEAAHGTVTRHYR 339

  Fly   379 FYQQGKETSTNPIASIFAWTRGLLHRAKLDNNEPLKQFADTLEQVCIDTIESGAMTKDLAICIKG 443
            .:|:|..||||||||||||||||.||..|||||.||.|:.|||:.||||:|.|.|||||:|||.|
 Worm   340 EHQKGNSTSTNPIASIFAWTRGLHHRGVLDNNEALKTFSLTLEKACIDTVEEGKMTKDLSICIHG 404

  Fly   444 NINAVTRRDYQETFEFINTL 463
            ......:..|..|.:|::.:
 Worm   405 TKKGTEKGAYLITEDFLSAI 424

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Idh	NP_001137910.2	PTZ00435	63..474	CDD:240417	266/403 (66%)
idh-2	NP_001370015.1	PTZ00435	25..434	CDD:240417	265/400 (66%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0538
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG62611
OrthoDB	1	1.010	-	-		D248894at33208
OrthoFinder	1	1.000	-	-		FOG0001185
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100639
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5145
SonicParanoid	1	1.000	-	-		X809
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	9	8.760