DRSC/TRiP Functional Genomics Resources

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Protein Alignment Idh and idh-2

DIOPT Version :10

Sequence 1:NP_001137910.2 Gene:Idh / 44291 FlyBaseID:FBgn0001248 Length:479 Species:Drosophila melanogaster
Sequence 2:NP_001370015.1 Gene:idh-2 / 181311 WormBaseID:WBGene00007942 Length:435 Species:Caenorhabditis elegans


Alignment Length:410 Identity:267/410 - (65%)
Similarity:319/410 - (77%) Gaps:2/410 - (0%)


- Green bases have known domain annotations that are detailed below.


  Fly    56 SVVCSPEQMAQKIKA-GPVVDVLGDEMTRIIWDSIKSQLILPFLDIELHTYDLGIENRDKTEDQV 119
            :|..:..|..||||. .||||:.|||||||||..||::||||:||:::..||||:|.||:|.|||
 Worm    15 NVATAATQERQKIKVDNPVVDLDGDEMTRIIWKEIKNKLILPYLDLDIKYYDLGLEYRDETNDQV 79

  Fly   120 TIDCAEAIKKYNVGIKCATITPDEKRVEEFNLKKMWKSPNGTIRNILGGTVFREAIICKNVPRLV 184
            |||.|.||.:::||||||||||||.|::||||||||.|||||||||||||||||.|:|||:||||
 Worm    80 TIDAAHAILEHSVGIKCATITPDEARIKEFNLKKMWLSPNGTIRNILGGTVFREPILCKNIPRLV 144

  Fly   185 TGWQKPIVIGRHAHADQYKAVDYVVPGPGKLTLTWKGTDGQVIDEVINDF-KGPGIALGMFNTDD 248
            .||.:||.|||||..||||..|.|:|....|.|.....||......:.|| |..|:.|.|:|||:
 Worm   145 PGWTQPITIGRHAFGDQYKCTDLVIPSGSTLQLLVNKPDGSKDVHNVYDFKKSGGVGLAMYNTDE 209

  Fly   249 SIVDFAHASFKYALDRKLPLYMSTKNTILKKYDGRFKDIFEDLYNKQYKKEYEAAGIWYEHRLID 313
            ||..|||:.|:|||.::.|||:||||||||||||||||||:|:|.|:|:.:::...|||||||||
 Worm   210 SIKGFAHSCFQYALMKQWPLYLSTKNTILKKYDGRFKDIFQDIYEKKYEADFKNNKIWYEHRLID 274

  Fly   314 DMVAYAMKSEGGFVWACKNYDGDVQSDSVAQGYGSLGLMTSVLLCPDGKTVEAEAAHGTVTRHFR 378
            |.||.|:||.|||||||||||||||||.|||||||||||:|||:||||||:||||||||||||:|
 Worm   275 DQVAQALKSSGGFVWACKNYDGDVQSDIVAQGYGSLGLMSSVLMCPDGKTIEAEAAHGTVTRHYR 339

  Fly   379 FYQQGKETSTNPIASIFAWTRGLLHRAKLDNNEPLKQFADTLEQVCIDTIESGAMTKDLAICIKG 443
            .:|:|..||||||||||||||||.||..|||||.||.|:.|||:.||||:|.|.|||||:|||.|
 Worm   340 EHQKGNSTSTNPIASIFAWTRGLHHRGVLDNNEALKTFSLTLEKACIDTVEEGKMTKDLSICIHG 404

  Fly   444 NINAVTRRDYQETFEFINTL 463
            ......:..|..|.:|::.:
 Worm   405 TKKGTEKGAYLITEDFLSAI 424

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
IdhNP_001137910.2 PTZ00435 63..474 CDD:240417 266/403 (66%)
idh-2NP_001370015.1 PTZ00435 25..434 CDD:240417 265/400 (66%)

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