DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment flw and PPT1

DIOPT Version :9

Sequence 1:	NP_727418.1	Gene:	flw / 44289	FlyBaseID:	FBgn0000711	Length:	461	Species:	Drosophila melanogaster
Sequence 2:	NP_011639.3	Gene:	PPT1 / 853023	SGDID:	S000003355	Length:	513	Species:	Saccharomyces cerevisiae

Alignment Length:	430	Identity:	138/430 - (32%)
Similarity:	199/430 - (46%)	Gaps:	79/430 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 DLNVDSLIQRLLENFKKQKEAEEHAQKLLIA--------QQLAAAGGASGASATSPTSSSNYSSM 61
            ||||      ||    |.|..:..|.|.|:.        :...|.|||...:..|...:.|.||.
Yeast   102 DLNV------LL----KAKPNDPAATKALLTCDRFIREERFRKAIGGAENEAKISLCQTLNLSSF 156

  Fly    62 AAVASFGSGYGSGSGAGAPGAGAGPGSSHDPLDDLTEQQRRLLQQYSISPPSETMISADGDQITV 126
            .|.|.. :.|            .||....:.|.|    .:...:...|...|:..||...:.:.:
Yeast   157 DANADL-ANY------------EGPKLEFEQLYD----DKNAFKGAKIKNMSQEFISKMVNDLFL 204

  Fly   127 HHPREEPKKSRLKLRDFFVAEFVRSCRTGKQVQMTEAEVRGLCLKSREIFLQQPILLELE----- 186
             ..:..|||        :||..:....|                    :|.|:|.::|||
Yeast   205 -KGKYLPKK--------YVAAIISHADT--------------------LFRQEPSMVELENNSTP 240

  Fly   187 -APLIICGDIHGQYTDLLRLF-EYGGFPPAANYLFLGDYVDRGKQSLETICLLLAYKIKYPENFF 249
             ..:.:|||.|||:.|:|.|| ::|...|...|||.||:||||..|.|...|....||.:|.|||
Yeast   241 DVKISVCGDTHGQFYDVLNLFRKFGKVGPKHTYLFNGDFVDRGSWSCEVALLFYCLKILHPNNFF 305

  Fly   250 LLRGNHECASINRIYGFYDECKRRYNVKLWKTFTDCFNCLPVAAIIDEKIFCCHGGLSPD----L 310
            |.|||||..::|:||||.||||.:|:.:::..|...|..||:|.:|:......||||..|    |
Yeast   306 LNRGNHESDNMNKIYGFEDECKYKYSQRIFNMFAQSFESLPLATLINNDYLVMHGGLPSDPSATL 370

  Fly   311 QGMEQIRRLMRPTDVPDTGLLCDLLWSDPDKDVQGWGENDRGVSFTFGVDVVSKFLNRHELDLIC 375
            ...:.|.|..:|   |..|...:|||:|| ::..|.|.:.||:...||.|:..:||..::|..|.
Yeast   371 SDFKNIDRFAQP---PRDGAFMELLWADP-QEANGMGPSQRGLGHAFGPDITDRFLRNNKLRKIF 431

  Fly   376 RAHQVVEDGYEFFARRQLVTLFSAPNYCGEFDNAGGMMTV 415
            |:|::...|.:|..:.:|:|:|||||||....|.||::.|
Yeast   432 RSHELRMGGVQFEQKGKLMTVFSAPNYCDSQGNLGGVIHV 471

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
flw	NP_727418.1	MPP_PP1_PPKL	149..428	CDD:277359	103/278 (37%)
flw	NP_727418.1	PP2Ac	160..430	CDD:197547	102/267 (38%)
PPT1	NP_011639.3	PLN03088	10..>130	CDD:215568	11/37 (30%)
		TPR repeat	12..40	CDD:276809
		TPR repeat	45..75	CDD:276809
		TPR repeat	80..108	CDD:276809	6/15 (40%)
		MPP_PP5_C	165..508	CDD:277362	117/356 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0639
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810