DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment flw and ppp5c

DIOPT Version :9

Sequence 1:	NP_727418.1	Gene:	flw / 44289	FlyBaseID:	FBgn0000711	Length:	461	Species:	Drosophila melanogaster
Sequence 2:	NP_001007891.1	Gene:	ppp5c / 493275	XenbaseID:	XB-GENE-982044	Length:	493	Species:	Xenopus tropicalis

Alignment Length:	324	Identity:	115/324 - (35%)
Similarity:	179/324 - (55%)	Gaps:	20/324 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly   118 SADGDQITVHHPREEPKKSRLKLRDFFVAEFVRSCRTGKQVQMTEAEVRGLCLKSREIFLQQPIL 182
            |.|.:.:|:......|:.....:...|:.|.::..:..|::.  ...|..:.::.::|..:.|.|
Frog   158 SLDIEGMTIEDEYTGPQLKDGNVTIDFMLELMQFYKDQKKLH--RKCVYQMLVQVKDILSKLPSL 220

  Fly   183 LEL----EAPLIICGDIHGQYTDLLRLFEYGGFPPAAN-YLFLGDYVDRGKQSLETICLLLAYKI 242
            :|:    ...:.:|||.|||:.||:.:|...|.|...| |:|.||:||||..|:|.|..|..:|:
Frog   221 VEISLEKSQQVTVCGDTHGQFYDLMNIFHLNGLPSENNPYIFNGDFVDRGSFSVEVIVTLFGFKL 285

  Fly   243 KYPENFFLLRGNHECASINRIYGFYDECKRRYNVKLWKTFTDCFNCLPVAAIIDEKIFCCHGGL- 306
            .||..|.|||||||..::|::|||..|.|.:|:.::::.|::.|..||:|..:::::...||||
Frog   286 LYPAQFHLLRGNHETDTMNQMYGFEGEVKAKYSAQMFQLFSEVFQWLPLAMCVNQRVLIMHGGLF 350

  Fly   307 SPDLQGMEQIRRLMRPTDVPDTGLLCDLLWSDPDKDVQGWGENDRGVSFTFGVDVVSKFLNRHEL 371
            |.|...::|||.:.|....||:|.:||||||||... .|...:.||||..||.||..:||..:.|
Frog   351 SEDGVTLDQIRSIERNRQPPDSGPMCDLLWSDPQPQ-DGRSSSKRGVSCQFGPDVTRRFLEENGL 414

  Fly   372 DLICRAHQVVEDGYEFFARRQLVTLFSAPNYCGEFDNAGGMMTVDDTLMCSFQILKPSEKKAKY 435
            |.|.|:|:|..:|||.......||:|||||||.:..|.|           ::..|..|:.|.|:
Frog   415 DYIIRSHEVKPEGYEVSHNGLCVTVFSAPNYCDQMGNKG-----------AYIHLNGSDLKPKF 467

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
flw	NP_727418.1	MPP_PP1_PPKL	149..428	CDD:277359	106/284 (37%)
flw	NP_727418.1	PP2Ac	160..430	CDD:197547	105/275 (38%)
ppp5c	NP_001007891.1	PLN03088	22..>232	CDD:330826	12/75 (16%)
		TPR repeat	22..50	CDD:276809
		TPR repeat	55..85	CDD:276809
		TPR repeat	90..118	CDD:276809
		MPP_PP5_C	170..485	CDD:277362	112/312 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910