DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment flw and Ppef1

DIOPT Version :9

Sequence 1:	NP_727418.1	Gene:	flw / 44289	FlyBaseID:	FBgn0000711	Length:	461	Species:	Drosophila melanogaster
Sequence 2:	XP_038955765.1	Gene:	Ppef1 / 317498	RGDID:	1562772	Length:	664	Species:	Rattus norvegicus

Alignment Length:	329	Identity:	107/329 - (32%)
Similarity:	157/329 - (47%)	Gaps:	42/329 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   156 KQVQMTEAE-VRGLCLKSREIFLQQPILLELEA----PLIICGDIHGQYTDLLRLFEYGGFPPAA 215
            ||.|...|. |..:..::|:|..|.|....::.    .:.||||:||:..||:.:|...|.|...
  Rat   154 KQQQTLHAHYVLEVLFEARKILKQMPNFTRIQTFPAKEITICGDLHGKLDDLMLIFYKNGLPSEK 218

  Fly   216 N-YLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNV--- 276
            | |:|.||:||||..|:|.:.:||...:.||.:..|.|||||...:|..|||..|..::|.:
  Rat   219 NPYVFNGDFVDRGNNSMEILMILLVSFLVYPTDLHLNRGNHEDFMMNLRYGFTKEILQKYKLHGK 283

  Fly   277 KLWKTFTDCFNCLPVAAIIDEKIFCCHGGL--SPDLQGMEQIRR------LMRPTDVPD------ 327
            |:.:...:.:..||:..|||.:|...|||:  |.||..::|::|      ||.|.....
  Rat   284 KILQVLEELYTWLPIGTIIDNEILVIHGGISESTDLNILQQLQRNKMKSVLMPPMSTNQECNIKK 348

  Fly   328 --------------TGL----LCDLLWSDPDKDVQGWGENDRGVSFTFGVDVVSKFLNRHELDLI 374
                          |.|    :.|||||||......:....||....||.||.||.||:::|.::
  Rat   349 NKAGPSEQSASEQLTKLEWEQIIDLLWSDPRGKKGCYPNTSRGGGCYFGPDVTSKVLNKNQLKMV 413

  Fly   375 CRAHQVVEDGYEFFARRQLVTLFSAPNYCGEFDNAGGMMTVD-DTLMCSFQILKPSEKKAKYLYS 438
            .|:|:...||||.....:::|:|||.||..|..|.|..:.:. .|....||....|......||.
  Rat   414 IRSHECKPDGYEICHDGKVITVFSASNYYEEGSNRGAYIRLSYGTSPQFFQYQVTSTSCLNPLYQ 478

  Fly   439 GMNS 442
            .:|:
  Rat   479 RVNA 482

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
flw	NP_727418.1	MPP_PP1_PPKL	149..428	CDD:277359	103/313 (33%)
flw	NP_727418.1	PP2Ac	160..430	CDD:197547	100/311 (32%)
Ppef1	XP_038955765.1	IQ	40..>57	CDD:197470
		MPP_RdgC	140..466	CDD:277364	103/311 (33%)
		PTZ00183	505..647	CDD:185503
		EF-hand_7	582..650	CDD:404394
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0639
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000018
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.810