DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment flw and Ppef2

DIOPT Version :9

Sequence 1:	NP_727418.1	Gene:	flw / 44289	FlyBaseID:	FBgn0000711	Length:	461	Species:	Drosophila melanogaster
Sequence 2:	XP_038947795.1	Gene:	Ppef2 / 305246	RGDID:	1307093	Length:	793	Species:	Rattus norvegicus

Alignment Length:	514	Identity:	124/514 - (24%)
Similarity:	192/514 - (37%)	Gaps:	148/514 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    88 SSHDPLDDLTEQQRRLLQQYSISPPSETMISADGDQITVHHPREEPKKSRLKLRDFFVAEFVRSC 152
            |||...|.|    .|:..:...:...||....|.:.|.|......|:.|...|.|...| .|.:.
  Rat   115 SSHHERDFL----NRMFTEERFAQDVETEEGGDFESIEVPDSYTGPRLSFPLLPDHATA-LVEAF 174

  Fly   153 RTGKQVQMTEAEVRGLCLKSREIFLQQPILLELEA----PLIICGDIHGQYTDLLRLFEYGGFP- 212
            |..:|:.  ...|..|..::|....|.|.:..:..    .:.:|||:|||..||:.:|...|.|
  Rat   175 RLRQQLH--ARYVLNLLYETRRHLAQLPNINRVSTCYSEEVTVCGDLHGQLDDLIFIFYKNGLPS 237

  Fly   213 PAANYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNV- 276
            |...|:|.||:|||||.|:|.:.:|.|:.:.||:.|.|.|||||...:|..|||..|...:|.:
  Rat   238 PERAYVFNGDFVDRGKDSVEVLMVLFAFMLVYPKEFHLNRGNHEDHLVNLRYGFTKEVMHKYKIH 302

  Fly   277 --KLWKTFTDCFNCLPVAAIIDEKIFCCHGG---------------------------------- 305
              |:.:|..|.|..||:|.::|||:...|||
  Rat   303 GKKILRTLQDVFCWLPLATLVDEKVLVLHGGVSDKTDLELLAKLDRHKIVSTMRCKTRKESENLE 367

  Fly   306 -----------------------------------------------------LSPDLQGMEQIR 317
                                                                 :|.:|....|:|
  Rat   368 EQKRKDNQTSSAQKPTPWFLPQSRSLPSSPFHLGSGFKAYKACRSCSIPCGSAVSKELSRQGQVR 432

  Fly   318 RLM-------------------------RPTDVPDTGLL----------CDLLWSDPDKDVQGWG 347
            |.|                         ...|....|:|          .|:|||||... :|..
  Rat   433 RSMDLELELCRQQAGFLGIREKRESLPLADCDADAGGMLKPTPEEWKQVVDILWSDPMAQ-EGCK 496

  Fly   348 END-RGVSFTFGVDVVSKFLNRHELDLICRAHQVVEDGYEFFARRQLVTLFSAPNYCGEFDNAGG 411
            .|. ||....||.||..:.:.:::|..:.|:|:...:||||...|:::|:|||.||.....|.|.
  Rat   497 ANTVRGGGCYFGPDVTEQLMEKYKLQFLIRSHECKPEGYEFCHNRKVLTIFSASNYYEVGSNRGA 561

  Fly   412 MMTVDDTL---MCSFQILKPS------EKKAKYLYSGMNSSRPTTPQRSAPMLATNKKK 461
            .:.:...|   :..:|..|.:      ::.::...|.:.:.|......|:.:|...:|:
  Rat   562 YVKLGPALTPHIVQYQANKATHRLTMRQRISRVEESALRALRQKLFAHSSDLLVEFRKR 620

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
flw	NP_727418.1	MPP_PP1_PPKL	149..428	CDD:277359	102/412 (25%)
flw	NP_727418.1	PP2Ac	160..430	CDD:197547	100/409 (24%)
Ppef2	XP_038947795.1	IQ	60..79	CDD:197470
		MPP_RdgC	161..577	CDD:277364	104/419 (25%)
		FRQ1	617..761	CDD:227455	1/4 (25%)
		EFh	697..762	CDD:238008
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000018
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.910