DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment flw and pzh1

DIOPT Version :9

Sequence 1:	NP_727418.1	Gene:	flw / 44289	FlyBaseID:	FBgn0000711	Length:	461	Species:	Drosophila melanogaster
Sequence 2:	NP_593373.1	Gene:	pzh1 / 2542255	PomBaseID:	SPAC57A7.08	Length:	515	Species:	Schizosaccharomyces pombe

Alignment Length:	419	Identity:	215/419 - (51%)
Similarity:	273/419 - (65%)	Gaps:	33/419 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    45 SGASATSPTS--SSNYSSMAAVASFGSGY-----GSGSGAGAPGAGAGPGSSHDPL----DDLTE 98
            ||.|:.||||  .||..:|.:.::..|.:     .|.|.|.:|.:...|.|| .|:    |..:|
pombe    92 SGNSSQSPTSPHPSNQPAMLSPSTAASQHHHHHSSSSSYAVSPTSPTSPTSS-GPIGSNFDSASE 155

  Fly    99 QQRRLLQQYSISP---PSETMISADGDQITVHHPREEPKKSRLKLRDFFVAEFVR---SCRTGKQ 157
            ....:..|....|   |:..:.|.|.|         :|:.......|..:...:.   |.::.|.
pombe   156 HNGPVYPQDQQGPVIIPNSAISSTDPD---------DPETVVSLNVDEMIQRLIHVGYSRKSSKS 211

  Fly   158 VQMTEAEVRGLCLKSREIFLQQPILLELEAPLIICGDIHGQYTDLLRLFEYGGFPPAANYLFLGD 222
            |.:..||:..:|:..|||||.||.||||..|:.|.||:||||:||:||||..||||::|||||||
pombe   212 VCLKNAEITSICMAVREIFLSQPTLLELTPPVKIVGDVHGQYSDLIRLFEMCGFPPSSNYLFLGD 276

  Fly   223 YVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNVKLWKTFTDCFN 287
            ||||||||||||.||..|||:|||||||||||||||:|.|:||||||||||.|:|:||||.:.||
pombe   277 YVDRGKQSLETILLLFLYKIRYPENFFLLRGNHECANITRVYGFYDECKRRCNIKIWKTFINTFN 341

  Fly   288 CLPVAAIIDEKIFCCHGGLSPDLQGMEQIRRLMRPTDVPDTGLLCDLLWSDPDKDVQGWGENDRG 352
            |||:|:::..||||.||||||.|..|:.||.:.|||||||.|||.|||||||......|.:|:||
pombe   342 CLPIASVVAGKIFCVHGGLSPSLSHMDDIREIPRPTDVPDYGLLNDLLWSDPADTENDWEDNERG 406

  Fly   353 VSFTFGVDVVSKFLNRHELDLICRAHQVVEDGYEFFARRQLVTLFSAPNYCGEFDNAGGMMTVDD 417
            |||.|..:|:.:||.:|:.|||||||.|||||||||..|.|.|:||||||||||||.|.:|:|:.
pombe   407 VSFVFNKNVIRQFLAKHDFDLICRAHMVVEDGYEFFNDRTLCTVFSAPNYCGEFDNWGAVMSVNS 471

  Fly   418 TLMCSFQILKPSEKKA------KYLYSGM 440
            .|:|||:::||.::.|      |...|||
pombe   472 ELLCSFELIKPLDQAAIRRELKKSKRSGM 500

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
flw	NP_727418.1	MPP_PP1_PPKL	149..428	CDD:277359	179/281 (64%)
flw	NP_727418.1	PP2Ac	160..430	CDD:197547	178/269 (66%)
pzh1	NP_593373.1	PTZ00480	190..486	CDD:185658	182/295 (62%)
pzh1	NP_593373.1	MPP_PP1_PPKL	191..482	CDD:277359	180/290 (62%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0639
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000018
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100222
Panther	1	1.100	-	-	O	PTHR11668
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.810