DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment flw and SPBC3F6.01c

DIOPT Version :9

Sequence 1:	NP_727418.1	Gene:	flw / 44289	FlyBaseID:	FBgn0000711	Length:	461	Species:	Drosophila melanogaster
Sequence 2:	NP_596740.1	Gene:	SPBC3F6.01c / 2541004	PomBaseID:	SPBC3F6.01c	Length:	473	Species:	Schizosaccharomyces pombe

Alignment Length:	436	Identity:	139/436 - (31%)
Similarity:	210/436 - (48%)	Gaps:	55/436 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    40 AAGGASGASATSPTSSSNY--SSMAAVASFGSGYGSGSGAGAPGAGAGPGSSHDPLDDLTEQQRR 102
            |...||.|....|..:..|  .:.|.:|.|......|....|........::...|.:..:..:|
pombe    58 AINDASKAIECDPEYAKAYFRRATAHIAIFQPKEAVGDFRKALALAPSDPAARKKLRECEQLVKR 122

  Fly   103 LLQQYSI---SPPS-------ETM-ISADGDQITVHHPREEPKKSRLKLRDFFVAEFV-----RS 151
            :..|.:|   .|||       |.| |.:|.|.:.              |......|||     |.
pombe   123 IRFQEAIHNTEPPSPLANINIEDMDIPSDYDGVI--------------LEKQITKEFVEDMKERF 173

  Fly   152 CRTGKQVQMTEAE--VRGLCLKSREIFLQQPILLEL----EAPLIICGDIHGQYTDLLRLFEYGG 210
            |: ||::.:..|.  :|.|    :|:..:.|.|:::    :..|:||||.||||.|||.:|:..|
pombe   174 CQ-GKKLPLKFAYSILRDL----KELLEKTPSLIDIPVKGDETLVICGDTHGQYFDLLNIFKLHG 233

  Fly   211 FP-PAANYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRY 274
            .| |...|||.||:||||..|.|....|.|||:.||:..|:.|||||...:|::|||..||:.:|
pombe   234 PPSPTNKYLFNGDFVDRGSWSTEVAFTLYAYKLLYPDAVFINRGNHETDDMNKVYGFEGECRSKY 298

  Fly   275 NVKLWKTFTDCFNCLPVAAIIDEKIFCCHGGL-SPDLQGMEQIRRLMR--PTDVPDTGLLCDLLW 336
            |.:.:..|::.|:.||:.::|.:.....|||| |.|...::|:|.:.|  ......:||:.::||
pombe   299 NERTFNIFSETFSLLPLGSLISDSYLVVHGGLFSDDNVTLDQLRNIDRFSKKQPGQSGLMMEMLW 363

  Fly   337 SDPDKDVQGWGENDRGVSFTFGVDVVSKFLNRHELDLICRAHQVVEDGYEFFARRQLVTLFSAPN 401
            :|| :...|.|.:.|||...||.||..:|...:.|..:.|:|:|.:.|||.......:|:|||||
pombe   364 TDP-QPAPGRGPSKRGVGLQFGPDVSKRFCEANGLKAVIRSHEVRDQGYEVEHDGYCITVFSAPN 427

  Fly   402 YCGEFDNAGGMMTVDDTLMCSFQ----ILKPSEKKAKY---LYSGM 440
            ||....|.|.::.|.:.:...|.    :..|:.:...|   |.|||
pombe   428 YCDSTGNLGAVIKVKEDMELDFHQFEAVPHPNIRPMAYANGLLSGM 473

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
flw	NP_727418.1	MPP_PP1_PPKL	149..428	CDD:277359	107/297 (36%)
flw	NP_727418.1	PP2Ac	160..430	CDD:197547	103/283 (36%)
SPBC3F6.01c	NP_596740.1	TPR_11	4..70	CDD:290150	4/11 (36%)
		TPR repeat	5..33	CDD:276809
		TPR_11	38..104	CDD:290150	11/45 (24%)
		TPR repeat	38..68	CDD:276809	4/9 (44%)
		TPR_2	73..106	CDD:285020	6/32 (19%)
		TPR repeat	73..101	CDD:276809	6/27 (22%)
		MPP_PP5_C	152..467	CDD:277362	113/334 (34%)
		PP2Ac	184..456	CDD:197547	102/276 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0639
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810