DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment flw and hcfc2

DIOPT Version :9

Sequence 1:	NP_727418.1	Gene:	flw / 44289	FlyBaseID:	FBgn0000711	Length:	461	Species:	Drosophila melanogaster
Sequence 2:	XP_004912959.2	Gene:	hcfc2 / 100127587	XenbaseID:	XB-GENE-991080	Length:	833	Species:	Xenopus tropicalis

Alignment Length:	101	Identity:	25/101 - (24%)
Similarity:	40/101 - (39%)	Gaps:	28/101 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   157 QVQMTEAEVRGLCLKSREIFLQQPILLELE------------APLIICGDIH------GQYTDLL 203
            |||:.:|......||..|:...:..:|:|.            |||.....::      |.|:..|
Frog   419 QVQLIQATTNSFHLKWDELPTVEGYILQLNPESPASSIAGTPAPLSEISALNQGNGRSGDYSTTL 483

  Fly   204 RLFEYG--GFPPAANYLFLGDYVDRGKQSLETICLL 237
            .||:.|  |...|      ||..:..:|::.  |:|
Frog   484 PLFQTGLLGSGEA------GDCQESPQQAVN--CIL 511

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
flw	NP_727418.1	MPP_PP1_PPKL	149..428	CDD:277359	25/101 (25%)
flw	NP_727418.1	PP2Ac	160..430	CDD:197547	22/98 (22%)
hcfc2	XP_004912959.2	PLN02193	<67..383	CDD:177844
		KELCH repeat	81..119	CDD:276965
		KELCH repeat	131..181	CDD:276965
		KELCH repeat	185..245	CDD:276965
		KELCH repeat	248..299	CDD:276965
		KELCH repeat	303..369	CDD:276965
		FN3	<658..689	CDD:238020
		FN3	695..795	CDD:238020
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910