| Sequence 1: | NP_524737.2 | Gene: | arr / 44279 | FlyBaseID: | FBgn0000119 | Length: | 1678 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | XP_005259002.1 | Gene: | LRP3 / 4037 | HGNCID: | 6695 | Length: | 785 | Species: | Homo sapiens |
| Alignment Length: | 563 | Identity: | 137/563 - (24%) |
|---|---|---|---|
| Similarity: | 191/563 - (33%) | Gaps: | 184/563 - (32%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 1227 WLDDKTGVERITVN-----------------GERRSAELQRLPQITDIRAVWTPDPKVLRNHTCM 1274
Fly 1275 HSRTKCSHICIASGEGIARTRDV---CSCPKHLMLLEDKENCGAFPACGPDHFTCAAPVSGISDV 1336
Fly 1337 NKDCIPASWRCDGQKDCPDKSDEVGCPTCRADQFSCQ--SGECIDKSLVCDGTTNCANGHDEADC 1399
Fly 1400 --CKRPGEFQCPINKLCISAALLCDGWENCADGADESSDICLQRRMAPATDKRAFMILIGATMIT 1462
Fly 1463 IFSIVYL-----LQFCRTRIGKSRTEPKDDQATDPLSPSTLSKS--------------------- 1501
Fly 1502 -QRVSK--IASVAD-----AVRMSTL-NSRNSMNSYDRNH------------------------- 1532
Fly 1533 ------ITGA-SSSTTNGSSMVAYPINPPPSPATRSRRPYRHYKIINQPPPPTPCSTDICDESDS 1590
Fly 1591 NYTSKSNSNNSNGGATKHSSSSA--------AACLQYGYD----SEPYPPPPTPRSHYHSDVRIV 1643
Fly 1644 PESSCPPSP--SSRSSTYF----SPL-----PPPP-SPVQSPS 1674 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| arr | NP_524737.2 | LY | 162..201 | CDD:214531 | |
| NHL | 168..503 | CDD:302697 | |||
| NHL repeat | 172..237 | CDD:271320 | |||
| LY | 252..293 | CDD:214531 | |||
| NHL repeat | 261..298 | CDD:271320 | |||
| NHL repeat | 303..339 | CDD:271320 | |||
| NHL repeat | 341..419 | CDD:271320 | |||
| NHL repeat | 428..476 | CDD:271320 | |||
| LY | 472..511 | CDD:214531 | |||
| NHL repeat | 477..503 | CDD:271320 | |||
| Ldl_recept_b | 534..573 | CDD:278487 | |||
| LY | 558..599 | CDD:214531 | |||
| LY | 600..641 | CDD:214531 | |||
| FXa_inhibition | 668..703 | CDD:291342 | |||
| LY | 739..773 | CDD:214531 | |||
| LY | 776..818 | CDD:214531 | |||
| LY | 819..860 | CDD:214531 | |||
| FXa_inhibition | 973..1010 | CDD:291342 | |||
| LY | 1122..1164 | CDD:214531 | |||
| FXa_inhibition | 1273..1313 | CDD:291342 | 8/42 (19%) | ||
| LDLa | 1319..1362 | CDD:238060 | 10/42 (24%) | ||
| LDLa | 1365..1399 | CDD:238060 | 12/35 (34%) | ||
| LDLa | 1399..1433 | CDD:197566 | 17/35 (49%) | ||
| LRP3 | XP_005259002.1 | CUB | 43..156 | CDD:238001 | |
| LDLa | 166..200 | CDD:238060 | |||
| LDLa | 212..249 | CDD:238060 | |||
| CUB | 254..364 | CDD:238001 | 18/86 (21%) | ||
| LDLa | 416..452 | CDD:238060 | 12/35 (34%) | ||
| LDLa | 455..489 | CDD:238060 | 18/37 (49%) | ||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 1 | 0.930 | - | - | C165155339 | |
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E1_KOG1215 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 0 | 0.000 | Not matched by this tool. | |||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 2 | 1.830 | |||||