Protein Alignment arr and cue

DIOPT Version :10

• Sequence 1: NP_524737.2
• Gene: arr / 44279
• FlyBaseID: FBgn0000119
• Length: 1678
• Species: Drosophila melanogaster
• Sequence 2: NP_612113.2
• Gene: cue / 38174
• FlyBaseID: FBgn0011204
• Length: 644
• Species: Drosophila melanogaster
• Alignment Length: 419
• Identity: 101/419 - (24%)
• Similarity: 163/419 - (38%)
• Gaps: 114/419 - (27%)

  Fly   438 AIDYDPVEEHIYWSDVE-----TYTIKRAHADGTGVTDFVTSEVRHPD--GLALDWLARNLYWTD 495
            |:.:|..||.||::|::     .:::||.......|.:...:...:..  |||.|.|..||:|:|
  Fly    63 ALTFDESEELIYFNDLKHRNGSIFSLKRDLIAANHVAEQTIARTGNESVGGLAYDPLNMNLFWSD 127

  Fly   496 TVTDRIEVCRLDGTARKVLIYEHLEE---PRAIAVAPSLGWMFWSDWNERKPKVERASLDGSERV 557
            |...:|....:.|:|...::.:...|   |..:||......::|::.|...|.|||.:||||.|.
  Fly   128 TEQRKIFFAPIHGSATPQVLVDLSAEGGRPDGVAVDVCRRKLYWTNSNVTHPTVERINLDGSNRT 192

  Fly   558 VLVSENLGWPNGIALDIEAKAIYWCD---GKTDKIEVANMDGSGRRVVISDNLKHLFGLSILDDY 619
            |::|.|:..|.||.:|..:..::|.|   |....:|.:.:|||.|:||:.|.......|::.:|.
  Fly   193 VIISSNIDMPRGIVVDQLSDRLFWIDDLKGVFFSVESSKLDGSDRQVVLKDKHHEPLNLAVTNDA 257

  Fly   620 LYWTDWQRRSIDRAH------KITGNNR---------IVVVDQYP---DLMGLKVTRL-REVRGQ 665
            :||||...|:: .:|      |:|..::         ....|..|   |...::|..| .|.||
  Fly   258 IYWTDRTTRAV-WSHPKVPVIKVTTTSKPDEEDSTDSTDFKDPEPVAEDCPLVRVANLSEEARG- 320

  Fly   666 NACAVRNGGCSHLCLNRPRDYVC----------------------------------RCAID--Y 694
              ...|.|....|    .:|:.|                                  ||..|  |
  Fly   321 --IVARTGFYQRL----QKDHHCASIVRKVKERVDEQSRKFEIRSLLDQKIKVLEDERCMNDGEY 379

  Fly   695 ELANDKRTCVVPAAFLLFSRQEHIGRISIEYNEGNHNDERIPFKDVRDAHALDVSVAERRIYWTD 759
            ..|.|  .|:.|..|                 :|:.       .::|:.|       ...::.|.
  Fly   380 RAATD--LCICPTGF-----------------KGSR-------CEIRECH-------NYCVHGTC 411

  Fly   760 QKS-----KCIFRAFLNGSYVQRIVDSGL 783
            |.|     ||..:....|...:..|.|||
  Fly   412 QMSELAYPKCYCQPGFKGERCELSVCSGL 440

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
arr	NP_524737.2	LY	162..201	CDD:214531
		NHL	168..503	CDD:302697	21/71 (30%)
		NHL repeat	172..237	CDD:271320
		LY	252..293	CDD:214531
		NHL repeat	261..298	CDD:271320
		NHL repeat	303..339	CDD:271320
		NHL repeat	341..419	CDD:271320
		NHL repeat	428..476	CDD:271320	10/42 (24%)
		LY	472..511	CDD:214531	12/40 (30%)
		NHL repeat	477..503	CDD:271320	11/27 (41%)
		Ldl_recept_b	534..574	CDD:459654	17/39 (44%)
		LY	558..599	CDD:214531	14/43 (33%)
		LY	600..641	CDD:214531	13/46 (28%)
		FXa_inhibition	668..703	CDD:464251	11/70 (16%)
		YncE	<736..886	CDD:442618	12/53 (23%)
		LY	776..818	CDD:214531	4/8 (50%)
		LY	905..946	CDD:214531
		FXa_inhibition	973..1010	CDD:464251
		YncE	<1047..1191	CDD:442618
		LDLa	1319..1362	CDD:238060
		LDLa	1365..1399	CDD:238060
		LDLa	1399..1433	CDD:197566
cue	NP_612113.2	TerD_like	48..>85	CDD:473128	7/21 (33%)
		YvrE	<73..>164	CDD:442613	23/90 (26%)
		LY	101..141	CDD:214531	11/39 (28%)
		Ldl_recept_b	167..208	CDD:459654	17/40 (43%)
		LY	193..237	CDD:214531	14/43 (33%)