Protein Alignment arr and nid2a

DIOPT Version :9

• Sequence 1: NP_524737.2
• Gene: arr / 44279
• FlyBaseID: FBgn0000119
• Length: 1678
• Species: Drosophila melanogaster
• Sequence 2: XP_005169904.1
• Gene: nid2a / 322921
• ZFINID: ZDB-GENE-030827-2
• Length: 1804
• Species: Danio rerio
• Alignment Length: 276
• Identity: 97/276 - (35%)
• Similarity: 146/276 - (52%)
• Gaps: 21/276 - (7%)

  Fly   386 PTGVKLISANTCANGSQEMMFIVQRTQISKISLDSPDYTIFPLPL-GKVKYAIAIDYDPVEEHIY 449
            |||..|:    .|.|.|..:..:..||:.|      :.:...|.| |.:  .:.||||..|..:|
Zfish  1539 PTGTSLL----YAQGQQIGVLPLNGTQMDK------ERSSVLLALHGSI--VVGIDYDCRERKVY 1591

  Fly   450 WSDVETYTIKRAHAD-GTGVTDFVTSEVRHPDGLALDWLARNLYWTDTVTDRIEVCRLDGTARKV 513
            |:|:...||.||..| |:.....:.:.:..|:|||:|...|.|:|.|:..|:||...|||:.|.|
Zfish  1592 WTDLAGRTINRASLDPGSEPEIIINTALTSPEGLAVDVARRRLFWVDSTLDKIETANLDGSDRHV 1656

  Fly   514 LIYEHLEEPRAIAVAPSLGWMFWSDWNERKPKVERASLDGSERVVLVSENLGWPNGIALDIEAKA 578
            |....|..|||:.|..|.|.::|:|||...||:|.:|:||..|.|||.|.:|.||.:..|...:.
Zfish  1657 LFATDLVNPRAMIVDSSTGTLYWTDWNREAPKIESSSVDGQNRRVLVQEGIGLPNALTYDSTMRQ 1721

  Fly   579 IYWCDGKTDKIEVANMDGSGRRVVISDNLKHLFGLSILDDYLYWTDWQRR---SIDRAHKITGNN 640
            :.|.|..|.::|..:.:|:||| ||..||.:.|.:....::.|:|||:|.   |:.|.:::|..
Zfish  1722 VCWADAGTKRLECISPNGTGRR-VIQSNLNYPFSMVYFANHYYYTDWRRDGVISLGRDNQLTDE- 1784

  Fly   641 RIVVVDQYPDLMGLKV 656
              .:.||...|.|:.|
Zfish  1785 --YLPDQRSHLYGITV 1798

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
arr	NP_524737.2	LY	162..201	CDD:214531
		NHL	168..503	CDD:302697	38/118 (32%)
		NHL repeat	172..237	CDD:271320
		LY	252..293	CDD:214531
		NHL repeat	261..298	CDD:271320
		NHL repeat	303..339	CDD:271320
		NHL repeat	341..419	CDD:271320	10/32 (31%)
		NHL repeat	428..476	CDD:271320	17/49 (35%)
		LY	472..511	CDD:214531	15/38 (39%)
		NHL repeat	477..503	CDD:271320	11/25 (44%)
		Ldl_recept_b	534..573	CDD:278487	18/38 (47%)
		LY	558..599	CDD:214531	13/40 (33%)
		LY	600..641	CDD:214531	14/43 (33%)
		FXa_inhibition	668..703	CDD:291342
		LY	739..773	CDD:214531
		LY	776..818	CDD:214531
		LY	819..860	CDD:214531
		FXa_inhibition	973..1010	CDD:291342
		LY	1122..1164	CDD:214531
		FXa_inhibition	1273..1313	CDD:291342
		LDLa	1319..1362	CDD:238060
		LDLa	1365..1399	CDD:238060
		LDLa	1399..1433	CDD:197566
nid2a	XP_005169904.1	NIDO	113..278	CDD:214712
		EGF_3	442..470	CDD:289699
		nidG2	474..697	CDD:238158
		EGF_3	710..746	CDD:289699
		EGF_CA	748..790	CDD:214542
		EGF_3	799..828	CDD:289699
		Thyroglobulin_1	839..905	CDD:278514
		Thyroglobulin_1	915..978	CDD:278514
		Thyroglobulin_1	991..1054	CDD:278514
		Thyroglobulin_1	1067..1130	CDD:278514
		Thyroglobulin_1	1143..1206	CDD:278514
		Thyroglobulin_1	1219..1282	CDD:278514
		Thyroglobulin_1	1295..1358	CDD:278514
		Thyroglobulin_1	1371..1434	CDD:278514
		TY	1453..1518	CDD:238114
		LY	1569..1606	CDD:214531	15/38 (39%)
		LY	1612..1654	CDD:214531	15/41 (37%)
		LY	1655..1699	CDD:214531	19/43 (44%)
		LY	1700..1742	CDD:214531	13/41 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170590469
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.930