Protein Alignment arr and egf

DIOPT Version :9

• Sequence 1: NP_524737.2
• Gene: arr / 44279
• FlyBaseID: FBgn0000119
• Length: 1678
• Species: Drosophila melanogaster
• Sequence 2: NP_001106478.1
• Gene: egf / 100127663
• XenbaseID: XB-GENE-951823
• Length: 1051
• Species: Xenopus tropicalis
• Alignment Length: 874
• Identity: 190/874 - (21%)
• Similarity: 325/874 - (37%)
• Gaps: 277/874 - (31%)

  Fly    84 NTPAT-LLFTTRHDIQVANITRPTGGPQIDVIVRDLAEAMAIDFYYAKNLVCWTDSGREIIECAQ 147
            |||.. |:|:..:||...|    :.|..:..:|......:.|||...:|.:.|.|..|..::...
 Frog    43 NTPVPFLIFSHGNDIFTIN----SDGTNLRKVVPSAGSTLQIDFIQQENRLYWLDQNRGFLQRMY 103

  Fly   148 TNSSALQPLLRAPKQTVISTGLDKPEGLAMDWYTDKIYWTDGEKNRIEVATLDGRYQKVLFWTDL 212
            .|.|..:.|....|.::         |.|:||..:.|:|.:.:|..||:.:.:.:..:||. ..|
 Frog   104 LNGSKHERLRAVGKGSI---------GFAIDWKHNVIFWANQQKGTIELTSRNEKRSRVLL-RGL 158

  Fly   213 DQPRAVAVVPARKLLIWTDWGEYPKIERASMDGDPLSRMTLVKEHVFWPNGLAVDLKNELIYW-- 275
            ..|:.||:.|...||.|:....:..|::|::||   |.:|.:.|......||.:|..::.|:|
 Frog   159 FNPKFVAIDPLEGLLFWSSNKSWTIIQKATLDG---SNVTSIIELSGALKGLTLDTDDKKIFWIL 220

  Fly   276 --TDGKHHFIDVMRLDGSSRRTIVNNLK-----YPFSLTFYDDRLYWTDWQRGSLNALD------ 327
              .|.:...|.....:|.| ..||.||:     :...::...:.:|:::.:.||:..::
 Frog   221 SKIDREDSVIGSCSYNGDS-VMIVKNLRLSTKYHVLGVSLLYNHIYYSERKSGSIKVINKFTGKD 284

  Fly   328 ----------LQTRELKEL--IDTPKAPNS----------------------------------- 345
                      ::.|.:|.:  :.:...|||
 Frog   285 IVSVNLKPSIMEIRNIKVVYPVRSYSIPNSSSNQGAKSCSISNKHCTKTCEIDAENQKCHCMNGF 349

  Fly   346 --------------VRAWDPS---------------------LQP-----YEDNP-------CAH 363
                          ...|:..                     |.|     ::..|       |:|
 Frog   350 VLSSNGRYCEDINECALWNHGCTLGCENIPGSYFCTCPEGYVLLPDNKTCHDKTPCLTEHIECSH 414

  Fly   364 --------------------------------NNGNCSHLCLLATNSQGFSCACPTGVKL-ISAN 395
                                            :||.|||:|:: :....:.|.|..|..| :...
 Frog   415 GCVQTTKGPLCTCPEGSVLSEDGKSCTGCTSPDNGGCSHICIM-SGPGTWECDCFPGYNLQLDRK 478

  Fly   396 TC-ANGSQEMMFIVQRTQISKISLDSPDY-TIFPLPLGKVKYAIAIDYDPVEEHIYWSDVETYTI 458
            .| |:|.:..:.......|.:|:.|..:| ::....:|:|   .|:||||||:.:|::......|
 Frog   479 QCLASGPRPYLMFANVHDIRRINFDGTNYESVLDSQIGRV---FALDYDPVEDRMYFAHTALKCI 540

  Fly   459 KRAHADGTGVTDFVTSEVRHPDGLALDWLARNLYWTDTVTDRIEVCRLDGTARKVLIYEHLEEPR 523
            :.|:.||:.....::.::...:||.:|.:.|.|||||.....||...|:|..||:||.|:..:||
 Frog   541 ESANMDGSDRKKMISGDLSTLEGLTVDAINRKLYWTDRGKSCIERSDLNGKYRKILIQENNIQPR 605

  Fly   524 AIAVAPSLGWMFWSDWNERKPKVERASLDGSERVVLVSENLGWPNGIALDIEAKAIYWCDGKTDK 588
            .|.|.|....:||:... ..|::|.:.|:||||.|::|::|.||:||.:|.....|||||.|...
 Frog   606 GICVHPLAKKLFWTHVG-ANPRIESSDLEGSEREVIISKDLIWPSGITVDHLTDVIYWCDAKKSV 669

  Fly   589 IEVANMDGSGRRVVISDNLKHLFGLSILDDYLYWTDWQRRSIDRAHKITGNNRI----------- 642
            ||.||:|||.|:....:::.|.|.:|:.:|:|:.:||.:.|:.|..|....|.:
 Frog   670 IESANLDGSNRQSFSQNDVGHPFAISVFEDHLWVSDWVQPSLIRIEKRNTQNWVRLRGNMQRPSS 734

  Fly   643 ----------VVVDQYP-----------------DLMGLKVTRLREVRGQNACAVRNG------- 673
                      |:.|..|                 ...|...|...|:..:.|.:.|||
 Frog   735 VVIVHPLAKPVIADDIPLPRKEKDSNNQTAHSESFFPGPLSTSNAEMGTREAPSSRNGLLAEIMV 799

  Fly   674 ----GCSHL-------------------------------------------------CLNRPRD 685
                ||..:                                                 |::....
 Frog   800 SDDSGCIDIHCDINAHCVSSEDGPKCQCLEGFTGNGRLCHDIDECSLHIAACNPHQTECIDTEGG 864

  Fly   686 YVCRCAIDY-----------ELANDKRTC 703
            |:|:|...|           |.:....||
 Frog   865 YICKCKYGYIGNGLQCTDIDECSRGTHTC 893

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
arr	NP_524737.2	LY	162..201	CDD:214531	9/38 (24%)
		NHL	168..503	CDD:302697	94/478 (20%)
		NHL repeat	172..237	CDD:271320	19/64 (30%)
		LY	252..293	CDD:214531	10/44 (23%)
		NHL repeat	261..298	CDD:271320	10/40 (25%)
		NHL repeat	303..339	CDD:271320	5/53 (9%)
		NHL repeat	341..419	CDD:271320	24/193 (12%)
		NHL repeat	428..476	CDD:271320	14/47 (30%)
		LY	472..511	CDD:214531	13/38 (34%)
		NHL repeat	477..503	CDD:271320	10/25 (40%)
		Ldl_recept_b	534..573	CDD:278487	16/38 (42%)
		LY	558..599	CDD:214531	21/40 (53%)
		LY	600..641	CDD:214531	10/40 (25%)
		FXa_inhibition	668..703	CDD:291342	11/105 (10%)
		LY	739..773	CDD:214531
		LY	776..818	CDD:214531
		LY	819..860	CDD:214531
		FXa_inhibition	973..1010	CDD:291342
		LY	1122..1164	CDD:214531
		FXa_inhibition	1273..1313	CDD:291342
		LDLa	1319..1362	CDD:238060
		LDLa	1365..1399	CDD:238060
		LDLa	1399..1433	CDD:197566
egf	NP_001106478.1	LY	152..194	CDD:214531	15/45 (33%)
		vWFA	<346..398	CDD:320736	3/51 (6%)
		FXa_inhibition	412..440	CDD:317114	2/27 (7%)
		FXa_inhibition	447..480	CDD:317114	10/33 (30%)
		LY	508..550	CDD:214531	14/44 (32%)
		LY	554..593	CDD:214531	13/38 (34%)
		Ldl_recept_b	615..654	CDD:278487	16/39 (41%)
		LY	638..680	CDD:214531	21/41 (51%)
		EGF_3	810..838	CDD:315598	0/27 (0%)
		EGF_3	851..880	CDD:315598	5/28 (18%)
		EGF_3	886..>914	CDD:315598	2/8 (25%)
		PHA02887	<927..>967	CDD:333467

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910