DRSC/TRiP Functional Genomics Resources

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Protein Alignment SoxN and Sox11

DIOPT Version :10

Sequence 1:NP_001260269.1 Gene:SoxN / 44275 FlyBaseID:FBgn0029123 Length:761 Species:Drosophila melanogaster
Sequence 2:NP_445801.1 Gene:Sox11 / 84046 RGDID:69351 Length:395 Species:Rattus norvegicus


Alignment Length:334 Identity:100/334 - (29%)
Similarity:138/334 - (41%) Gaps:66/334 - (19%)


- Green bases have known domain annotations that are detailed below.


  Fly   179 VKRPMNAFMVWSRGQRRKMASDNPKMHNSEISKRLGAQWKDLSESEKRPFIDEAKRLRAVHMKEH 243
            :|||||||||||:.:|||:...:|.|||:|||||||.:||.|.:|||.|||.||:|||..||.::
  Rat    49 IKRPMNAFMVWSKIERRKIMEQSPDMHNAEISKRLGKRWKMLKDSEKIPFIREAERLRLKHMADY 113

  Fly   244 PDYKYRPRRKTKTLTKTKEKYPMGGLMPGQTVGGG----APGEPVTPTRVQGQPGQNQSLNGSGG 304
            ||||||||:|.||....|   |..|..|.::..|.    .||:.....:...         |..|
  Rat   114 PDYKYRPRKKPKTDPAAK---PSAGQSPDKSAAGAKAAKGPGKKCAKLKAPA---------GKAG 166

  Fly   305 SAAAAAAAAAAAAQQAR-------------QDMYQMNAPNGYMPNGYMMHADPAGA------AAY 350
            :..||......|.:.|:             .|..|:..    .|:......:||.:      |..
  Rat   167 AGKAAQPGDCGAGKAAKCVFLDDDDEEDDEDDELQLRP----KPDADDDDDEPAHSHLLPPPAQQ 227

  Fly   351 QTSYMGQHYAAQRYDMGHMYNNGYAMYQTVSGGQTSPYGSSLQ---QPGSPSPYGGSSLQQQPGS 412
            |...:.:.|:..:....          .|:|....||.|:||.   :.|....|...::.:|...
  Rat   228 QPPQLLRRYSVAKVPAS----------PTLSSAAESPEGASLYDEVRAGGRLYYSFKNITKQQPP 282

  Fly   413 PTPYGGGGGGGGQVSCQSHSPSDSSIKSEPVSPSPSAIALNNNNNINNNHIMKREYSSAAAAAAA 477
            |.|..........||..|.|.|.|...:|........::||              :|..|.:|..
  Rat   283 PAPPALSPASSRCVSTSSSSGSSSGSGAEDADDLMFDLSLN--------------FSQGAHSACE 333

  Fly   478 AAAAAAAGG 486
            ....|.|.|
  Rat   334 QPLGAGAAG 342

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
SoxNNP_001260269.1 HMG-box_SoxB 177..252 CDD:438790 48/72 (67%)
Sox11NP_445801.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..22
HMG-box_SoxC_SOX11 38..129 CDD:438846 52/79 (66%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 114..258 37/169 (22%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 276..312 9/35 (26%)
Required for transcriptional activation activity and synergistic coactivation of transcriptional activity with POU3F2. /evidence=ECO:0000250|UniProtKB:Q7M6Y2 363..395
Blue background indicates that the domain is not in the aligned region.

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