DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment SoxN and SOX14

DIOPT Version :9

Sequence 1:NP_001260269.1 Gene:SoxN / 44275 FlyBaseID:FBgn0029123 Length:761 Species:Drosophila melanogaster
Sequence 2:NP_004180.1 Gene:SOX14 / 8403 HGNCID:11193 Length:240 Species:Homo sapiens


Alignment Length:311 Identity:118/311 - (37%)
Similarity:148/311 - (47%) Gaps:87/311 - (27%)


- Green bases have known domain annotations that are detailed below.


  Fly   176 ADRVKRPMNAFMVWSRGQRRKMASDNPKMHNSEISKRLGAQWKDLSESEKRPFIDEAKRLRAVHM 240
            :|.:|||||||||||||||||||.:|||||||||||||||:||.|||:||||:|||||||||.||
Human     5 SDHIKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLSEAEKRPYIDEAKRLRAQHM 69

  Fly   241 KEHPDYKYRPRRKTKTLTKTKEKY--PMGGLMPGQTVGGGAPGEPVTPTRVQGQPGQNQSLNGSG 303
            |||||||||||||.|.|.| |::|  |:..|  |.|          .|.:..|.|          
Human    70 KEHPDYKYRPRRKPKNLLK-KDRYVFPLPYL--GDT----------DPLKAAGLP---------- 111

  Fly   304 GSAAAAAAAAAAAAQQARQDMYQMNAPNGYMPNGYMMHADPAGAAAYQTSYMGQHYAAQRYDMGH 368
               ..|:....:|.::||..:...:||...:        |||..::.....||        ::.|
Human   112 ---VGASDGLLSAPEKARAFLPPASAPYSLL--------DPAQFSSSAIQKMG--------EVPH 157

  Fly   369 MYNNGYAMYQTVSGGQTSPYGSSLQQPGS-----PSPYGGSSLQQQPGSPTPYGGGGGGGGQVSC 428
            ....|...|.:..|.|...:| ||..|..     |||       ..||...|          .:|
Human   158 TLATGALPYASTLGYQNGAFG-SLSCPSQHTHTHPSP-------TNPGYVVP----------CNC 204

  Fly   429 QSHSPSDSSIKSEPVS----PSPSAIALNNNNNINNNHIMKREYSSAAAAA 475
            .:.|   :|....||:    |..:...::             .||||.|.|
Human   205 TAWS---ASTLQPPVAYILFPGMTKTGID-------------PYSSAHATA 239

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
SoxNNP_001260269.1 SOX-TCF_HMG-box 178..249 CDD:238684 61/70 (87%)
SOX14NP_004180.1 SOX-TCF_HMG-box 7..78 CDD:238684 61/70 (87%)
SOXp 77..>118 CDD:403523 19/66 (29%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG0527
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 1 1.000 - - FOG0000028
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR10270
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
43.910

Return to query results.
Submit another query.